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Warren Kruger

Email
Center AffiliationsCancer Biology

Publications (90) (print view)

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Gallego-Villar L, Hannibal L, Haberle J, Thony B, Ben-Omran T, Nasrallah GK, Dewik AN, Kruger WD, Blom HJ. Cysteamine revisited: repair of arginine to cysteine mutations. J Inherit Metab Dis. 2017 Jul;40(4):555-67.
Gupta S, Wang L, Kruger WD. The c.797 G>A (p.R266K) cystathionine beta-synthase mutation causes homocystinuria by affecting protein stability. Hum Mutat. 2017 Jul;38(7):863-9.   PMCID: PMC5525156
Khayati K, Antikainen H, Bonder EM, Weber GF, Kruger WD, Jakubowski H, Dobrowolski R. The amino acid metabolite homocysteine activates mTORC1 to inhibit autophagy and form abnormal proteins in human neurons and mice. Faseb j. 2017 Feb;31(2):598-609.
Kruger WD. Cystathionine beta-synthase deficiency: Of mice and men. Molecular genetics and metabolism. 2017 Jul;121(3):199-205.   PMCID: PMC5526210
Lee HO, Uzzo RG, Kister D, Kruger WD. Combination of serum histidine and plasma tryptophan as a potential biomarker to detect clear cell renal cell carcinoma. Journal of translational medicine. 2017 Apr 06;15(1):72.   PMCID: PMC5383954
Lee HO, Uzzo RG, Kister D, Kruger WD. Combination of serum histidine and plasma tryptophan as a potential biomarker to detect clear cell renal cell carcinoma. Journal of translational medicine. 2017 Apr 06;15(1):72.   PMCID: PMC5383954
Lee HO, Wang L, Kuo YM, Gupta S, Slifker MJ, Li YS, Andrews AJ, Kruger WD. Lack of global epigenetic methylation defects in CBS deficient mice. J Inherit Metab Dis. 2017 Jan;40(1):113-20.   PMCID: PMC5300059
Lee HO, Wang LQ, Kuo YM, Gupta S, Slifker MJ, Li YS, Andrews AJ, Kruger WD. Lack of global epigenetic methylation defects in CBS deficient mice. Journal of Inherited Metabolic Disease. 2017 Jan;40(1):113-20.
Lee HO, Wang LQ, Kuo YM, Gupta S, Slifker MJ, Li YS, Andrews AJ, Kruger WD. Lack of global epigenetic methylation defects in CBS deficient mice. Journal of Inherited Metabolic Disease. 2017 Jan;40(1):113-20.   PMCID: PMC5300059
Li JG, Barrero C, Gupta S, Kruger WD, Merali S, Pratico D. Homocysteine modulates 5-lipoxygenase expression level via DNA methylation. Aging cell. 2017 Apr;16(2):273-80.   PMCID: PMC5334532
Gupta S, Wang L, Kruger WD. Betaine supplementation is less effective than methionine restriction in correcting phenotypes of CBS deficient mice. J Inherit Metab Dis. 2016 Aug;39(1):39-46.   PMCID: 4784539
Kruger WD, Gupta S. The effect of dietary modulation of sulfur amino acids on cystathionine beta synthase-deficient mice. Ann N Y Acad Sci. 2016 Jan;1363(1):80-90.   PMCID: PMC4801721
Imbard A, Benoist JF, Esse R, Gupta S, Lebon S, de Vriese AS, de Baulny HO, Kruger W, Schiff M, Blom HJ. High homocysteine induces betaine depletion. Biosci Rep. 2015 Apr 28;35(4).   PMCID: 4613678
Lee HO, Mustafa A, Hudes GR, Kruger WD. Hydroxychloroquine Destabilizes Phospho-S6 in Human Renal Carcinoma Cells. PLoS One. 2015 Jan;10(7):e0131464.   PMCID: PMC4489871
Esse R, Imbard A, Florindo C, Gupta S, Quinlivan EP, Davids M, Teerlink T, de Almeida IT, Kruger WD, Blom HJ, Castro R. Protein arginine hypomethylation in a mouse model of cystathionine beta-synthase deficiency. Faseb Journal. 2014 Jun;28(6):2686-95.   PMCID: PMC4021445
Fang P, Zhang DQ, Cheng ZJ, Yan CH, Jiang XH, Kruger WD, Meng S, Arning E, Bottiglieri T, Choi ET, Han YL, Yang XF, Wang H. Hyperhomocysteinemia Potentiates Hyperglycemia-Induced Inflammatory Monocyte Differentiation and Atherosclerosis. Diabetes. 2014 Dec;63(12):4275-90.   PMCID: Pmc4237991
Gupta S, Melnyk SB, Kruger WD. Cystathionine beta-synthase-deficient mice thrive on a low-methionine diet. Faseb Journal. 2014 Feb;28(2):781-90.   PMCID: PMC3898656
Shlomi T, Fan J, Tang B, Kruger WD, Rabinowitz JD. Quantitation of cellular metabolic fluxes of methionine. Anal Chem. 2014 Feb 04;86(3):1583-91.   PMCID: 4060246
Tang B, Kadariya Y, Chen Y, Slifker M, Kruger WD. Expression of MTAP inhibits tumor-related phenotypes in HT1080 cells via a mechanism unrelated to its enzymatic function. G3 (Bethesda). 2014 Jan;5(1):35-44.   PMCID: 4291467
Gupta S, Wang LQ, Anderl J, Slifker MJ, Kirk C, Kruger WD. Correction of Cystathionine -Synthase Deficiency in Mice by Treatment with Proteasome Inhibitors. Human Mutation. 2013 Aug;34(8):1085-93.   PMCID: NIHMS 481408
The above publications are sorted by year, faculty last name, and first author. Click on any highlighted author listed to find all publications attributed to that individual. Click on the publication title to see the abstract. First authors who are faculty are highlighted like this. Last authors who are faculty are highlighted like this. Other authors who are faculty are highlighted like this.

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Last updated on Thursday, November 02, 2017