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Andres Klein-Szanto

Email
Center AffiliationsCancer Biology

Publications (222) (print view)

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Bassi DE, Zhang J, Renner C, Klein-Szanto AJ. Targeting proprotein convertases in furin-rich lung cancer cells results in decreased in vitro and in vivo growth. Mol Carcinog. 2017 Mar;56(3):1182-8.
Giroux V, Lento AA, Islam M, Pitarresi JR, Kharbanda A, Hamilton KE, Whelan KA, Long A, Rhoades B, Tang Q, Nakagawa H, Lengner CJ, Bass AJ, Wileyto EP, Klein-Szanto AJ, Wang TC, Rustgi AK. Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration. J Clin Invest. 2017 Jun;127(6):2378-91.   PMCID: PMC5451220
Klein-Szanto AJ, Bassi DE. Proprotein convertase inhibition: Paralyzing the cell's master switches. Biochemical pharmacology. 2017 Apr 26;140:8-15.
Tan Y, Sementino E, Xu J, Pei J, Liu Z, Ito TK, Cai KQ, Peri S, Klein-Szanto AJ, Wiest DL, Testa JR. The homeoprotein Dlx5 drives murine T-cell lymphomagenesis by directly transactivating Notch and upregulating Akt signaling. Oncotarget. 2017 Jan 21;.
Tan Y, Sementino E, Xu J, Pei J, Liu Z, Ito TK, Cai KQ, Peri S, Klein-Szanto AJ, Wiest DL, Testa JR. The homeoprotein Dlx5 drives murine T-cell lymphomagenesis by directly transactivating Notch and upregulating Akt signaling. Oncotarget. 2017 Feb 28;8(9):14941-56.   PMCID: PMC5362456
Whelan KA, Chandramouleeswaran PM, Tanaka K, Natsuizaka M, Guha M, Srinivasan S, Darling DS, Kita Y, Natsugoe S, Winkler JD, Klein-Szanto AJ, Amaravadi RK, Avadhani NG, Rustgi AK, Nakagawa H. Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance. Oncogene. 2017 Apr 17;36(34):4843-58.   PMCID: PMC5570661
Whelan KA, Merves JF, Giroux V, Tanaka K, Guo A, Chandramouleeswaran PM, Benitez AJ, Dods K, Que J, Masterson JC, Fernando SD, Godwin BC, Klein-Szanto AJ, Chikwava K, Ruchelli ED, Hamilton KE, Muir AB, Wang ML, Furuta GT, Falk GW, Spergel JM, Nakagawa H. Autophagy mediates epithelial cytoprotection in eosinophilic oesophagitis. Gut. 2017 Jul;66(7):1197-207.   PMCID: PMC4987278
Kadariya Y, Cheung M, Xu J, Pei J, Sementino E, Menges CW, Cai KQ, Rauscher FJ, Klein-Szanto AJ, Testa JR. Bap1 is a bona fide tumor suppressor: genetic evidence from mouse models carrying heterozygous germline Bap1 mutations. Cancer Res. 2016 Feb 19;76(9):2836-44.   PMCID: PMC4873414
Kadariya Y, Menges CW, Talarchek J, Cai KQ, Klein-Szanto AJ, Pietrofesa RA, Christofidou-Solomidou M, Cheung M, Mossman BT, Shukla A, Testa JR. Inflammation-Related IL-1beta/IL-1R Signaling Promotes the Development of Asbestos-Induced Malignant Mesothelioma. Cancer prevention research (Philadelphia, Pa). 2016 Mar 02;9(5):406-14.   PMCID: PMC4854753
Tanaka K, Whelan KA, Chandramouleeswaran PM, Kagawa S, Rustgi SL, Noguchi C, Guha M, Srinivasan S, Amanuma Y, Ohashi S, Muto M, Klein-Szanto AJ, Noguchi E, Avadhani NG, Nakagawa H. ALDH2 modulates autophagy flux to regulate acetaldehyde-mediated toxicity thresholds. Am J Cancer Res. 2016 Mar;6(4):781-96.   PMCID: PMC4859883
Tetreault MP, Weinblatt D, Ciolino JD, Klein-Szanto AJ, Sackey BK, Twyman-Saint Victor C, Karakasheva T, Teal V, Katz JP. Esophageal Expression of Active IkappaB kinase-beta in Mice Upregulates Tumor Necrosis Factor and Granulocyte Macrophage Colony-stimulating Factor, Promoting Inflammation and Angiogenesis. Gastroenterology. 2016 Feb 16;150(7):1609-1619 e11.   PMCID: PMC4909513
Wang Y, Cai KQ, Smith ER, Yeasky TM, Moore R, Ganjei-Azar P, Klein-Szanto AJ, Godwin AK, Hamilton TC, Xu XX. Follicle Depletion Provides A Permissive Environment for Ovarian Carcinogenesis. Mol Cell Biol. 2016 Jun 27;36(18):2418-30.   PMCID: PMC5007791
Albury TM, Pandey V, Gitto SB, Dominguez L, Spinel LP, Talarchek J, Klein-Szanto AJ, Testa JR, Altomare DA. Constitutively Active Akt1 Cooperates with KRas(G12D) to Accelerate In Vivo Pancreatic Tumor Onset and Progression. Neoplasia. 2015 Feb;17(2):175-82.   PMCID: PMC4351297
Bassi DE, Cenna J, Zhang J, Cukierman E, Klein-Szanto AJ. Enhanced aggressiveness of benzopyrene-induced squamous carcinomas in transgenic mice overexpressing the proprotein convertase PACE4 (PCSK6). Mol Carcinog. 2015 Oct;54(10):1122-31.   PMCID: PMC4240754
Bassi DE, Cenna J, Zhang J, Cukierman E, Klein-Szanto AJ. Enhanced aggressiveness of benzopyrene-induced squamous carcinomas in transgenic mice overexpressing the proprotein convertase PACE4 (PCSK6). Molecular Carcinogenesis. 2015 Jan;54(10):1122-31.
Fedele M, Visone R, De Martino I, Palmieri D, Valentino T, Esposito F, Klein-Szanto A, Arra C, Ciarmiello A, Croce CM, Fusco A. Erratum: Expression of a truncated Hmga1b gene induces gigantism, lipomatosis and B-cell lymphomas in mice (European Journal of Cancer (2011) 47 (470-478) (DOI: 10.1016/j.ejca.2010.09.045)). European Journal of Cancer. 2015 Jan;51(6):789.
Fu J, Zhang J, Gong Y, Testa CL, Klein-Szanto AJ. Regulation of HIF-1 Alpha by the Proprotein Convertases Furin and PC7 in Human Squamous Carcinoma Cells. Molecular Carcinogenesis. 2015 Sep;54(9):698-706.   PMCID: 4101078
Gabitova L, Restifo D, Gorin A, Manocha K, Handorf E, Yang DH, Cai KQ, Klein-Szanto AJ, Cunningham D, Kratz LE, Herman GE, Golemis EA, Astsaturov I. Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR. Cell Rep. 2015 Sep 22;12(11):1927-38.   PMCID: PMC4581991
Kagawa S, Natsuizaka M, Whelan KA, Facompre N, Naganuma S, Ohashi S, Kinugasa H, Egloff AM, Basu D, Gimotty PA, Klein-Szanto AJ, Bass AJ, Wong KK, Diehl JA, Rustgi AK, Nakagawa H. Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities. Oncogene. 2015 Apr 30;34(18):2347-59.   PMCID: 4268095
Lian Z, Lee EK, Bass AJ, Wong KK, Klein-Szanto AJ, Rustgi AK, Diehl JA. FBXO4 loss facilitates carcinogen induced papilloma development in mice. Cancer Biol Ther. 2015 May;16(5):750-5.   PMCID: 4622573
The above publications are sorted by year, faculty last name, and first author. Click on any highlighted author listed to find all publications attributed to that individual. Click on the publication title to see the abstract. First authors who are faculty are highlighted like this. Last authors who are faculty are highlighted like this. Other authors who are faculty are highlighted like this.

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Last updated on Wednesday, September 06, 2017