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Jonathan Chernoff

Email
Center AffiliationsCancer Biology

Publications (182) (print view)

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Araiza-Olivera D, Chernoff J. Hras helps hippo heterodimerize to evade tumor suppression. Small GTPases. 2018 Jul 04;9(4):327-31.   PMCID: PMC5997136
Araiza-Olivera D, Feng Y, Semenova G, Prudnikova TY, Rhodes J, Chernoff J. Suppression of RAC1-driven malignant melanoma by group A PAK inhibitors. Oncogene. 2018 Feb 15;37(7):944-52.   PMCID: PMC5814328
Chernoff J. How to get and keep your lab funded. Mol Biol Cell. 2018 Oct 15;29(21):2519-21.
Chow HY, Dong B, Valencia CA, Zeng CT, Koch JN, Prudnikova TY, Chernoff J. Group I Paks are essential for epithelial- mesenchymal transition in an Apc-driven model of colorectal cancer. Nat Commun. 2018 Aug 27;9(1):3473.   PMCID: PMC6110733
Karchugina S, Chernoff J. Detection of Heterodimerization of Protein Isoforms Using an in Situ Proximity Ligation Assay. Journal of visualized experiments : JoVE. 2018 Oct 20;(140).   PMCID: PMC6235567
Kim SM, Nguyen TT, Ravi A, Kubiniok P, Finicle BT, Jayashankar V, Malacrida L, Hou J, Robertson J, Gao D, Chernoff J, Digman MA, Potma EO, Tromberg BJ, Thibault P, Edinger AL. PTEN deficiency and AMPK activation promote nutrient scavenging and anabolism in prostate cancer cells. Cancer discovery. 2018 Jul;8(7):866-83.   PMCID: PMC6030497
Stepanova DS, Braun L, Chernoff J. A new concept in NF2 pharmacotherapy: targeting fatty acid synthesis. Oncoscience. 2018 May;5(5-6):126-7.   PMCID: PMC6049319
Chernoff J. Alfred G. Knudson Jr, MD, PhD: In Memoriam (1922-2016). Cancer Res. 2017 Feb 15;77(4):815-6.
Chernoff J, Radu M. Recent advances in methods to assess the activity of the kinome. F1000Research. 2017 Jun;6:1004.   PMCID: PMC5490475
Joseph GA, Lu M, Radu M, Lee JK, Burden SJ, Chernoff J, Krauss RS. Group I Paks Promote Skeletal Myoblast Differentiation In Vivo and In Vitro. Mol Cell Biol. 2017 Feb 15;37(4).   PMCID: PMC5288579
Lu H, Liu S, Zhang G, Bin W, Zhu Y, Frederick DT, Hu Y, Zhong W, Randell S, Sadek N, Zhang W, Chen G, Cheng C, Zeng J, Wu LW, Zhang J, Liu X, Xu W, Krepler C, Sproesser K, Xiao M, Miao B, Liu J, Song CD, Liu JY, Karakousis GC, Schuchter LM, Lu Y, Mills G, Cong Y, Chernoff J, Guo J, Boland GM, Sullivan RJ, Wei Z, Field J, Amaravadi RK, Flaherty KT, Herlyn M, Xu X, Guo W. PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas. Nature. 2017 Oct 05;550(7674):133-6.   PMCID: PMC5891348
Prudnikova TY, Chernoff J. The Group I Pak inhibitor Frax-1036 sensitizes 11q13-amplified ovarian cancer cells to the cytotoxic effects of Rottlerin. Small GTPases. 2017 Oct 02;8(4):193-8.   PMCID: PMC5680705
Radu M, Chernoff J. Recent advances in methods to assess the activity of the kinome. F1000Research. 2017 Jun;6:1004.   PMCID: PMC5490475
Semenova G, Chernoff J. Targeting PAK1. Biochemical Society transactions. 2017 Feb 08;45(1):79-88.
Semenova G, Stepanova D, Deyev SM, Chernoff J. Medium throughput biochemical compound screening identifies novel agents for pharmacotherapy of neurofibromatosis type I. Biochimie. 2017 Jan 05;135:1-5.   PMCID: PMC5405558
Semenova G, Stepanova D, Deyev SM, Chernoff J. Medium throughput biochemical compound screening identifies novel agents for pharmacotherapy of neurofibromatosis type I. Biochimie. 2017 Jan 05;.
Semenova G, Stepanova DS, Dubyk C, Handorf E, Deyev SM, Lazar AJ, Chernoff J. Targeting group I p21-activated kinases to control malignant peripheral nerve sheath tumor growth and metastasis. Oncogene. 2017 Sep 21;36(38):5421-31.   PMCID: PMC5608634
Stepanova DS, Semenova G, Kuo YM, Andrews AJ, Ammoun S, Hanemann CO, Chernoff J. An essential role for the tumor suppressor Merlin in regulating fatty acid synthesis. Cancer Res. 2017 Sep 15;77(18):5026-38.   PMCID: PMC5600854
Tan Y, Sementino E, Chernoff J, Testa JR. Targeting MYC sensitizes malignant mesothelioma cells to PAK blockage-induced cytotoxicity. American Journal of Cancer Research. 2017 Aug;7(8):1724-37.   PMCID: PMC5574944
Zeng K, Tian L, Sirek A, Shao W, Liu L, Chiang YT, Chernoff J, Ng DS, Weng J, Jin T. Pak1 mediates the stimulatory effect of insulin and curcumin on hepatic ChREBP expression. J Mol Cell Biol. 2017 Oct;9(5):384-94.   PMCID: PMC5907843
The above publications are sorted by year, faculty last name, and first author. Click on any highlighted author listed to find all publications attributed to that individual. Click on the publication title to see the abstract. First authors who are faculty are highlighted like this. Last authors who are faculty are highlighted like this. Other authors who are faculty are highlighted like this.

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Last updated on Tuesday, December 04, 2018