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Jonathan Chernoff

Email
Center AffiliationsCancer Biology

Publications (177) (print view)

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Araiza-Olivera D, Feng Y, Semenova G, Prudnikova TY, Rhodes J, Chernoff J. Suppression of RAC1-driven malignant melanoma by group A PAK inhibitors. Oncogene. 2018 Feb 15;37(7):944-52.   PMCID: PMC5814328
Kim SM, Nguyen TT, Ravi A, Kubiniok P, Finicle BT, Jayashankar V, Malacrida L, Hou J, Robertson J, Gao D, Chernoff J, Digman MA, Potma EO, Tromberg BJ, Thibault P, Edinger AL. PTEN deficiency and AMPK activation promote nutrient scavenging and anabolism in prostate cancer cells. Cancer discovery. 2018 Mar 23;.
Chernoff J. Alfred G. Knudson Jr, MD, PhD: In Memoriam (1922-2016). Cancer Res. 2017 Feb 15;77(4):815-6.
Chernoff J, Radu M. Recent advances in methods to assess the activity of the kinome. F1000Research. 2017 Jan;6:1004.   PMCID: PMC5490475
Joseph GA, Lu M, Radu M, Lee JK, Burden SJ, Chernoff J, Krauss RS. Group I Paks Promote Skeletal Myoblast Differentiation In Vivo and In Vitro. Mol Cell Biol. 2017 Feb 15;37(4).   PMCID: PMC5288579
Lu H, Liu S, Zhang G, Bin W, Zhu Y, Frederick DT, Hu Y, Zhong W, Randell S, Sadek N, Zhang W, Chen G, Cheng C, Zeng J, Wu LW, Zhang J, Liu X, Xu W, Krepler C, Sproesser K, Xiao M, Miao B, Liu J, Song CD, Liu JY, Karakousis GC, Schuchter LM, Lu Y, Mills G, Cong Y, Chernoff J, Guo J, Boland GM, Sullivan RJ, Wei Z, Field J, Amaravadi RK, Flaherty KT, Herlyn M, Xu X, Guo W. PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas. Nature. 2017 Oct 05;550(7674):133-6.
Radu M, Chernoff J. Recent advances in methods to assess the activity of the kinome. F1000Research. 2017 Jan;6:1004.   PMCID: PMC5490475
Semenova G, Chernoff J. Targeting PAK1. Biochemical Society transactions. 2017 Feb 08;45(1):79-88.
Semenova G, Stepanova D, Deyev SM, Chernoff J. Medium throughput biochemical compound screening identifies novel agents for pharmacotherapy of neurofibromatosis type I. Biochimie. 2017 Jan 05;135:1-5.   PMCID: PMC5405558
Semenova G, Stepanova D, Deyev SM, Chernoff J. Medium throughput biochemical compound screening identifies novel agents for pharmacotherapy of neurofibromatosis type I. Biochimie. 2017 Jan 05;.
Semenova G, Stepanova DS, Dubyk C, Handorf E, Deyev SM, Lazar AJ, Chernoff J. Targeting group I p21-activated kinases to control malignant peripheral nerve sheath tumor growth and metastasis. Oncogene. 2017 Sep 21;36(38):5421-31.   PMCID: PMC5608634
Stepanova DS, Semenova G, Kuo YM, Andrews AJ, Ammoun S, Hanemann CO, Chernoff J. An essential role for the tumor suppressor Merlin in regulating fatty acid synthesis. Cancer Res. 2017 Sep 15;77(18):5026-38.   PMCID: PMC5600854
Tan Y, Sementino E, Chernoff J, Testa JR. Targeting MYC sensitizes malignant mesothelioma cells to PAK blockage-induced cytotoxicity. American Journal of Cancer Research. 2017 Jan;7(8):1724-37.   PMCID: PMC5574944
Zeng K, Tian L, Sirek A, Shao W, Liu L, Chiang YT, Chernoff J, Ng DS, Weng J, Jin T. Pak1 mediates the stimulatory effect of insulin and curcumin on hepatic ChREBP expression. J Mol Cell Biol. 2017 Aug 18;9(5):384-94.
Zeng Y, Hahn S, Stokes J, Hoffman EA, Schmelz M, Proytcheva M, Chernoff J, Katsanis E. Pak2 regulates myeloid-derived suppressor cell development in mice. Blood advances. 2017 Oct 10;1(22):1923-33.   PMCID: PMC5728145 interests.
Araiza-Olivera D, Chernoff J. Hras helps hippo heterodimerize to evade tumor suppression. Small GTPases. 2016 Aug 25;:1-5.
Bellacosa A, Chernoff J, Testa JR. Alfred G. Knudson (1922-2016) Obituary. Cell. 2016 Aug;166(4):785-6.
Cruz OV, Prudnikova TY, Araiza-Olivera D, Perez-Plasencia C, Johnson N, Bernhardy AJ, Slifker M, Renner C, Chernoff J, Arias-Romero LE. Reduced PAK1 activity sensitizes FA/BRCA-proficient breast cancer cells to PARP inhibition. Oncotarget. 2016 Nov;7(47):76590-603.   PMCID: PMC5363532
Hu B, Arpag S, Zhang X, Mobius W, Werner H, Sosinsky G, Ellisman M, Zhang Y, Hamilton A, Chernoff J, Li J. Tuning PAK Activity to Rescue Abnormal Myelin Permeability in HNPP. PLoS Genet. 2016 Sep;12(9):e1006290.   PMCID: PMC5008806
Kurimchak AM, Shelton C, Duncan KE, Johnson KJ, Brown J, O'Brien S, Gabbasov R, Fink LS, Li Y, Lounsbury N, Abou-Gharbia M, Childers WE, Connolly DC, Chernoff J, Peterson JR, Duncan JS. Resistance to BET Bromodomain Inhibitors Is Mediated by Kinome Reprogramming in Ovarian Cancer. Cell Rep. 2016 Aug 02;16(5):1273-86.   PMCID: PMC4972668
The above publications are sorted by year, faculty last name, and first author. Click on any highlighted author listed to find all publications attributed to that individual. Click on the publication title to see the abstract. First authors who are faculty are highlighted like this. Last authors who are faculty are highlighted like this. Other authors who are faculty are highlighted like this.

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Last updated on Tuesday, June 05, 2018