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Alexei Tulin

Center AffiliationsCancer Biology

Publications (34) (print view)

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Makhov P, Uzzo RG, Tulin AV, Kolenko VM. Histone-dependent PARP-1 inhibitors: A novel therapeutic modality for the treatment of prostate and renal cancers. Urol Oncol. 2020 May 08;.
Karpova Y, Wu C, Divan A, McDonnell ME, Hewlett E, Makhov P, Gordon J, Ye M, Reitz AB, Childers WE, Skorski T, Kolenko V, Tulin AV. Non-NAD-like PARP-1 inhibitors in prostate cancer treatment. Biochemical pharmacology. 2019 Sep;167:149-62.   PMCID: PMC6702078
Nieborowska-Skorska M, Maifrede S, Ye M, Toma M, Hewlett E, Gordon J, Le BV, Sliwinski T, Zhao H, Piwocka K, Valent P, Tulin AV, Childers W, Skorski T. Non-NAD-like PARP1 inhibitor enhanced synthetic lethal effect of NAD-like PARP inhibitors against BRCA1-deficient leukemia. Leukemia & lymphoma. 2019 Apr;60(4):1098-101.   PMCID: PMC6445778
Thomas C, Ji Y, Wu C, Datz H, Boyle C, MacLeod B, Patel S, Ampofo M, Currie M, Harbin J, Pechenkina K, Lodhi N, Johnson SJ, Tulin AV. Hit and run versus long-term activation of PARP-1 by its different domains fine-tunes nuclear processes. Proc Natl Acad Sci U S A. 2019 May 14;116(20):9941-6.   PMCID: PMC6525528
Kotova E, Tulin AV. High-Throughput Colorimetric Assay for Identifying PARP-1 Inhibitors Using a Large Small-Molecule Collection. Methods Mol Biol. 2017 Jan;1608:299-312.
Naito S, Makhov P, Astsaturov I, Golovine K, Tulin A, Kutikov A, Uzzo RG, Kolenko VM. LDL cholesterol counteracts the antitumour effect of tyrosine kinase inhibitors against renal cell carcinoma. Br J Cancer. 2017 Apr 25;116(9):1203-7.   PMCID: PMC5418451
Thomas C, Kotova E, Tulin AV. PARP-1 Interaction with and Activation by Histones and Nucleosomes. Methods Mol Biol. 2017 Jan;1608:255-67.
Ji Y, Thomas C, Tulin N, Lodhi N, Boamah E, Kolenko V, Tulin AV. Charon Mediates Immune Deficiency-Driven PARP-1-Dependent Immune Responses in Drosophila. J Immunol. 2016 Aug 15;197(6):2382-9.   PMCID: PMC5010969
Ji Y, Tulin AV. Poly(ADP-ribosyl)ation of hnRNP A1 protein controls translational repression in Drosophila. Mol Cell Biol. 2016 Jul 11;36(19):2476-86.   PMCID: PMC5021380
Thomas C, Ji Y, Lodhi N, Kotova E, Pinnola AD, Golovine K, Makhov P, Pechenkina K, Kolenko V, Tulin AV. Non-NAD-Like poly(ADP-Ribose) Polymerase-1 Inhibitors effectively Eliminate Cancer in vivo. EBioMedicine. 2016 Nov;13:90-8.   PMCID: PMC5264309
Golovine K, Makhov P, Naito S, Raiyani H, Tomaszewski J, Mehrazin R, Tulin A, Kutikov A, Uzzo RG, Kolenko VM. Piperlongumine and its analogs down-regulate expression of c-Met in renal cell carcinoma. Cancer Biology & Therapy. 2015 May;16(5):743-9.   PMCID: 4623021
Kirsanov KI, Kotova E, Makhov P, Golovine K, Lesovaya EA, Kolenko VM, Yakubovskaya MG, Tulin AV. Minor grove binding ligands disrupt PARP-1 activation pathways. Oncotarget. 2014 Jan;5(2):428-37.   PMCID: PMC 3964218
Lodhi N, Kossenkov AV, Tulin AV. Bookmarking promoters in mitotic chromatin: poly(ADP-ribose)polymerase-1 as an epigenetic mark. Nucleic acids research. 2014 Jan;42(11):7028-38.   PMCID: PMC4066802
Makhov P, Golovine K, Teper E, Kutikov A, Mehrazin R, Corcoran A, Tulin A, Uzzo RG, Kolenko VM. Piperlongumine promotes autophagy via inhibition of Akt/mTOR signalling and mediates cancer cell death. Br J Cancer. 2014 Feb 18;110(4):899-907.   PMCID: PMC3929888
Thomas CJ, Kotova E, Andrake M, Adolf-Bryfogle J, Glaser R, Regnard C, Tulin AV. Kinase-mediated changes in nucleosome conformation trigger chromatin decondensation via poly(ADP-ribosyl)ation. Molecular cell. 2014 Mar 06;53(5):831-42.   PMCID: PMC3951681
Ji YB, Jarnik M, Tulin AV. Poly(ADP-ribose) glycohydrolase and poly(ADP-ribose)-interacting protein Hrp38 regulate pattern formation during Drosophila eye development. Gene. 2013 Sep;526(2):187-94.   PMCID: PMC 3729623
Ji Y, Jarnik M, Tulin AV. Poly(ADP-ribose) glycohydrolase and poly(ADP-ribose)-interacting protein Hrp38 regulate pattern formation during Drosophila eye development. Gene. 2013 Sep 10;526(2):187-94.   PMCID: Pmc3729623
Ji Y, Tulin AV. Post-Transcriptional Regulation by Poly(ADP-ribosyl)ation of the RNA-Binding Proteins. International journal of molecular sciences. 2013 Jan;14(8):16168-83.   PMCID: PMC 3759905
Thomas C, Tulin AV. Poly-ADP-ribose polymerase: Machinery for nuclear processes. Molecular Aspects of Medicine. 2013 Dec;34(6):1124-37.   PMCID: PMC 3750069
Boamah EK, Kotova E, Garabedian M, Jarnik M, Tulin AV. Poly(ADP-Ribose) Polymerase 1 (PARP-1) Regulates Ribosomal Biogenesis in Drosophila Nucleoli. PLoS Genet. 2012 Jan;8(1):e1002442.   PMCID: PMC3252306
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Last updated on Wednesday, July 08, 2020