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Publication Listing for the MeSH term p21-Activated Kinases. Found 14 abstracts

Lu H, Liu S, Zhang G, Bin W, Zhu Y, Frederick DT, Hu Y, Zhong W, Randell S, Sadek N, Zhang W, Chen G, Cheng C, Zeng J, Wu LW, Zhang J, Liu X, Xu W, Krepler C, Sproesser K, Xiao M, Miao B, Liu J, Song CD, Liu JY, Karakousis GC, Schuchter LM, Lu Y, Mills G, Cong Y, Chernoff J, Guo J, Boland GM, Sullivan RJ, Wei Z, Field J, Amaravadi RK, Flaherty KT, Herlyn M, Xu X, Guo W. PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas. Nature. 2017 Oct 05;550(7674):133-6.   PMCID: PMC5891348
Prudnikova TY, Chernoff J. The Group I Pak inhibitor Frax-1036 sensitizes 11q13-amplified ovarian cancer cells to the cytotoxic effects of Rottlerin. Small GTPases. 2017 Oct 02;8(4):193-8.   PMCID: PMC5680705
Prudnikova TY, Villamar-Cruz O, Rawat SJ, Cai KQ, Chernoff J. Effects of p21-activated kinase 1 inhibition on 11q13-amplified ovarian cancer cells. Oncogene. 2016 Apr 28;35(17):2178-85.   PMCID: PMC5125076
Reddy PN, Radu M, Xu K, Wood J, Harris CE, Chernoff J, Williams DA. P21 activated kinase 2 regulates HSPC cytoskeleton, migration and homing via CDC42 activation and interaction with beta-Pix. Blood. 2016 Mar;127(16):1967-75.   PMCID: PMC4841040
O'Hagan KL, Choi J, Pryshchep O, Chernoff J, Phee H. Pak2 Links TCR Signaling Strength to the Development of Regulatory T Cells and Maintains Peripheral Tolerance. J Immunol. 2015 Aug 15;195(4):1564-77.   PMCID: 4530067
Radu M, Lyle K, Hoeflich KP, Villamar-Cruz O, Koeppen H, Chernoff J. p21-activated kinase 2 (Pak2) regulates endothelial development and function through Bmk1/Erk5 pathway. Mol Cell Biol. 2015 Sep 21;35(23):3990-4005.   PMCID: PMC4628059
Chiang YT, Ip W, Shao W, Song ZE, Chernoff J, Jin T. Activation of cAMP signaling attenuates impaired hepatic glucose disposal in aged male p21-activated protein kinase-1 knockout mice. Endocrinology. 2014 Jun;155(6):2122-32.   PMCID: NO NIH funding
Itakura A, Aslan JE, Kusanto BT, Phillips KG, Porter JE, Newton PK, Nan XL, Insall RH, Chernoff J, McCarty OJ. p21-Activated Kinase (PAK) Regulates Cytoskeletal Reorganization and Directional Migration in Human Neutrophils. Plos One. 2013 Sep;8(9):e73063.   PMCID: PMC 3760889
Kelly ML, Chernoff J. Getting smart about p21-activated kinases. Mol Cell Biol. 2011 Feb;31(3):386-7.   PMCID: 3028629
Arias-Romero LE, Villamar-Cruz O, Pacheco A, Kosoff R, Huang M, Muthuswamy SK, Chernoff J. A Rac-Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells. Oncogene. 2010 Oct 28;29(43):5839-49.   PMCID: PMC2965784
Pacheco A, Chernoff J. Group I p21-activated kinases: emerging roles in immune function and viral pathogenesis. Int J Biochem Cell Biol. 2010 Jan;42(1):13-6.   PMCID: PMC2787825
Viaud J, Peterson JR. An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently. Mol Cancer Ther. 2009 Sep;8(9):2559-65.   PMCID: 2782767
Arias-Romero LE, Chernoff J. A tale of two Paks. Biol Cell. 2008 Feb;100(2):97-108.
Beeser A, Chernoff J. Production and use of a cell permeable inhibitor of group A Paks (TAT-PID) to analyze signal transduction. Methods (San Diego, Calif). 2005 Oct;37(2):203-7.
The above publications are sorted by year, faculty last name, and first author. Click on any highlighted author listed to find all publications attributed to that individual. Click on the publication title to see the abstract. First authors who are faculty are highlighted like this. Last authors who are faculty are highlighted like this. Other authors who are faculty are highlighted like this.

MeSH cloud from publications including the MeSH term p21-Activated Kinases

p21-Activated Kinases metabolism genetics Signal Transduction pharmacology Mice Female pathology enzymology chemistry drug effects antagonists & inhibitors Knockout Mice Male Tumor Cell Line Cytoskeleton cytology Cell Proliferation Protein Kinase Inhibitors Enzyme Activation MAP Kinase Signaling System Inbred C57BL Mice immunology Pyrazines SCID Mice Cell Movement Fluorescent Antibody Technique Xenograft Model Antitumor Assays physiology Cultured Cells deficiency inhibitors biosynthesis Western Blotting cdc42 GTP-Binding Protein Ovarian Neoplasms Rho Guanine Nucleotide Exchange Factors Glucagon-Like Peptide 1 Biological Models tat Gene Products Neutrophils Proto-Oncogene Proteins c-raf Peripheral Tolerance Cyclic AMP Inbred NOD Mice therapy Mitogen-Activated Protein Kinase 7 Liver etiology Glucose Protein Transport Endothelium signal transduction Cell Differentiation Mitogen-Activated Protein Kinases Protein-Serine-Threonine Kinases Phosphorylation Tumor Suppressor Protein p53 Virus Diseases methods Neoplastic Gene Expression Regulation TOR Serine-Threonine Kinases Allosteric Regulation Regulatory T-Lymphocytes Escherichia coli Cell Survival Thymus Gland RNA Interference Pyrimidines p21 inactivated kinase Neoplasm Drug Resistance Proto-Oncogene Proteins c-akt Phenotype Cardiovascular Abnormalities Cardiovascular System Triazoles Intestinal Mucosa Fluorescence Spectrometry Apoptosis Capillary Permeability antagonists & Cell Membrane Permeability Acetophenones Cell Cycle Colitis ovarian cancer Mutation Forkhead Transcription Factors Human Chromosomes-Pair 11 Melanoma Human Umbilical Vein Endothelial Cells Proto-Oncogene Proteins B-raf protein kinase Indirect Fluorescent Antibody Technique Real-Time Polymerase Chain Reaction oncogene Embryo Loss Gene Expression Profiling Antigen Receptors-T-Cell Drug Synergism blood Cell Communication Brain Recombinant Fusion Proteins Homeostasis Cell Cycle Checkpoints JNK Mitogen-Activated Protein Kinases Peptide Fragments Breast Neoplasms Fluorescence Microscopy COS Cells Benzopyrans Tissue Array Analysis Stem Cell Niche Cercopithecus aethiops erbB-2 Receptor Naphthols Hematopoietic Stem Cells Mitogen-Activated Protein Kinase Kinases Cell Line drug therapy Genetic Transduction Immunophenotyping Neoplastic Cell Transformation Binding Sites rac1 GTP-Binding Protein antagonists & Disulfides N-Formylmethionine Leucyl-Phenylalanine embryology Cyclin B1 Hepatocytes Immunohistochemistry chromosomal amplification Mammalian Embryo Gene Deletion Leukocyte Chemotaxis sensitized screen Developmental Gene Expression Regulation Enzyme Inhibitors Extracellular Signal-Regulated MAP Kinases T-Lymphocyte Subsets Piperidines Substrate Specificity Colforsin beta Catenin
Last updated on Thursday, April 02, 2020