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Publication Listing for the MeSH term integrase. Found 14 abstracts

Balasubramanian S, Rajagopalan M, Bojja RS, Skalka AM, Andrake MD, Ramaswamy A. The conformational feasibility for the formation of reaching dimer in ASV and HIV integrase: a molecular dynamics study. Journal of biomolecular structure & dynamics. 2016 Nov 28;:1-17.
Patel D, Antwi J, Koneru PC, Serrao E, Forli S, Kessl JJ, Feng L, Deng N, Levy RM, Fuchs JR, Olson AJ, Engelman AN, Bauman JD, Kvaratskhelia M, Arnold E. A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain. The Journal of biological chemistry. 2016 Nov 04;291(45):23569-77.   PMCID: PMC5095411
Andrake MD, Skalka AM. Retroviral Integrase: Then and Now. Annual review of virology. 2015 Nov;2(1):241-64.   PMCID: PMC4810031
Asante-Appiah E, Seeholzer SH, Skalka AM. Structural determinants of metal-induced conformational changes in HIV-1 integrase. Journal of Biological Chemistry. 1998 Dec 25;273(52):35078-87.
Katz RA, Gravuer K, Skalka AM. A preferred target DNA structure for retroviral integrase in vitro. Journal of Biological Chemistry. 1998 Sep 11;273(37):24190-5.
Lubkowski J, Yang F, Alexandratos J, Wlodawer A, Zhao H, Burke TR, Neamati N, Pommier Y, Merkel G, Skalka AM. Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 1998 Apr 28;95(9):4831-6.
Asante-Appiah E, Skalka AM. Molecular mechanisms in retrovirus DNA integration. Antiviral Research. 1997 Dec;36(3):139-56.
Andrake MD, Skalka AM. Retroviral integrase, putting the pieces together. Journal of Biological Chemistry. 1996 Aug 16;271(33):19633-6.
Katz RA, Merkel G, Skalka AM. Targeting of retroviral integrase by fusion to a heterologous DNA binding domain: In vitro activities and incorporation of a fusion protein into viral particles. Virology. 1996 Mar;217(1):178-90.
Bujacz G, Jaskoski M, Alexandratos J, Wlodawer A, Merkel G, Katz RA, Skalka AM. High-Resolution Structure of the Catalytic Domain of Avian- Sarcoma Virus Integrase. Journal of Molecular Biology. 1995 Oct 20;253(2):333-46.
Kukolj G, Skalka AM. Enhanced and Coordinated Processing of Synapsed Viral-DNA Ends by Retroviral Integrases in-Vitro. Genes & Development. 1995 Oct 15;9(20):2556-67.
Muller B, Bizubbender D, Andrake MD, Jones KS, Skalka AM. Monoclonal-Antibodies against Rous-Sarcoma Virus Integrase Protein Exert Differential-Effects on Integrase Function in- Vitro. Journal of Virology. 1995 Sep;69(9):5631-9.
Kulkosky J, Skalka AM. Molecular Mechanism of Retroviral DNA Integration. Pharmacology & Therapeutics. 1994 Jan;61(1-2):185-203.
Katz RA, Mack JP, Merkel G, Kulkosky J, Zheng G, Leis J, Skalka AM. Requirement for a Conserved Serine in Both Processing and Joining Activities of Retroviral Integrase. Proceedings of the National Academy of Sciences of the United States of America. 1992 Aug;89(15):6741-5.
The above publications are sorted by year, faculty last name, and first author. Click on any highlighted author listed to find all publications attributed to that individual. Click on the publication title to see the abstract. First authors who are faculty are highlighted like this. Last authors who are faculty are highlighted like this. Other authors who are faculty are highlighted like this.

MeSH cloud from publications including the MeSH term integrase

integrase viral-dna hiv-1 escherichia-coli protein human-immunodeficiency-virus invitro dna-binding integration retroviral murine leukemia-virus retrovirus crystal-structure reaching dimer identification reverse-transcriptase type-1 sequences site selection in-vitro catalytic domain aids hiv dna-binding domain avian-sarcoma substrate-binding X-ray crystallography X-Ray Crystallography photo-cross-linking zinc-binding type-1 integrase cruciform structures concerted drug screening site-specific recombination retroviral integrase carboxyl-terminal domains HIV-1 integrase polynucleotidyl transfer core dimer recognition amino-acid ltr lexa RSV - Rous Sarcoma Virus specificity nuclear- mutations HIV - Human Immunodeficiency Virus bacteriophage mu PFV - Prototype Foamy Virus drug effects macromolecular structures Hiv-1 prophage CTD - C-terminal domain recombinant proteins dimerization 3-dimensional structure CCD - Catalytic Core domain Allosteric Regulation HEK293 Cells localization signal region transposition SAXS - small angle X-ray scattering HIV Infections virology domains HIV Integrase Inhibitors core-core dimer cleavage human immunodeficiency virus (HIV) termini hiv-1 integrase medicinal chemistry NTD - N-terminal domain Drug Discovery v(d)j recombination supercoiled dna DNA - deoxyribo nucleic acid immunodeficiency-virus type-1 Hiv diffraction metabolism avian- viral- active-site anomalous diffraction Molecular Docking Simulation retroviral dna integration proviral recombination invitro integration multiwavelength anomalous sequence i- pol pharmacology ASV - Avian Sarcoma Virus allosteric inhibitor drug discovery chemistry IN - Integrase Thiophenes sarcoma hypersensitive sites x-ray structure multimerization ribonuclease-h directs integration provirus virus type-1 integrase dna fragment screening coli MMTV - Mouse Mammary Tumor Virus Molecular Models asv drug therapy HIV-1 intasome Carboxylic Acids Catalytic Domain HIV Integrase Asv structure comparison escherichia-
Last updated on Wednesday, September 06, 2017