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Publication Listing for the MeSH term Site-Directed Mutagenesis. Found 24 abstracts

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Mizukami T, Xu M, Fazlieva R, Bychkova VE, Roder H. Complex Folding Landscape of Apomyoglobin at Acidic pH Revealed by Ultrafast Kinetic Analysis of Core Mutants. J Phys Chem B. 2018 Aug 31;122(49):11228-39.   PMCID: PMC6395567
Markham GD, Takusagawa F, Dijulio AM, Bock CW. An investigation of the catalytic mechanism of S-adenosylmethionine synthetase by QM/MM calculations. Archives of biochemistry and biophysics. 2009 Dec;492(1-2):82-92.   PMCID: PMC2788016
Pietsch EC, Perchiniak E, Canutescu AA, Wang G, Dunbrack RL, Murphy ME. Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain. The Journal of biological chemistry. 2008 Jul 25;283(30):21294-304.   PMCID: PMC2475706
Maki K, Cheng H, Dolgikh DA, Roder H. Folding kinetics of staphylococcal nuclease studied by tryptophan engineering and rapid mixing methods. J Mol Biol. 2007 Apr 20;368(1):244-55.
Rennefahrt UE, Deacon SW, Parker SA, Devarajan K, Beeser A, Chernoff J, Knapp S, Turk BE, Peterson JR. Specificity profiling of Pak kinases allows identification of novel phosphorylation sites. The Journal of biological chemistry. 2007 May 25;282(21):15667-78.
Holmqvist PH, Belikov S, Zaret KS, Wrange O. FoxA1 binding to the MMTV LTR modulates chromatin structure and transcription. Exp Cell Res. 2005 Apr;304(2):593-603.
Isken O, Grassmann CW, Yu H, Behrens SE. Complex signals in the genomic 3' nontranslated region of bovine viral diarrhea virus coordinate translation and replication of the viral RNA. Rna-A Publication of the Rna Society. 2004 Oct;10(10):1637-52.
Taylor JC, Markham GD. Conformational dynamics of the active site loop of S-adenosylmethionine synthetase illuminated by site-directed spin labeling. Archives of biochemistry and biophysics. 2003 Jul 15;415(2):164-71.
Yusa S, Catina TL, Campbell KS. SHP-1- and phosphotyrosine-independent inhibitory signaling by a killer cell Ig-like receptor cytoplasmic domain in human NK cells. J Immunol. 2002 May 15;168(10):5047-57.
Eliash T, Weiner L, Ottolenghi M, Sheves M. Specific binding sites for cations in bacteriorhodopsin. Biophysical journal. 2001 Aug;81(2):1155-62.   PMCID: 1301584
Jaffe EK, Martins J, Li J, Kervinen J, Dunbrack RL. The molecular mechanism of lead inhibition of human porphobilinogen synthase. The Journal of biological chemistry. 2001 Jan 12;276(2):1531-7.
Kervinen J, Jaffe EK, Stauffer F, Neier R, Wlodawer A, Zdanov A. Mechanistic basis for suicide inactivation of porphobilinogen synthase by 4,7-dioxosebacic acid, an inhibitor that shows dramatic species selectivity. Biochemistry. 2001 Jul 27;40(28):8227-36.
Mitchell LW, Volin M, Martins J, Jaffe EK. Mechanistic implications of mutations to the active site lysine of porphobilinogen synthase. The Journal of biological chemistry. 2001 Jan 12;276(2):1538-44.
Mota M, Reeder M, Chernoff J, Bazenet CE. Evidence for a role of mixed lineage kinases in neuronal apoptosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2001 Jul 15;21(14):4949-57.
O'Neill GM, Golemis EA. Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics. Mol Cell Biol. 2001 Aug;21(15):5094-108.
Kervinen J, Dunbrack RL, Litwin S, Martins J, Scarrow RC, Volin M, Yeung AT, Yoon E, Jaffe EK. Porphobilinogen synthase from pea: expression from an artificial gene, kinetic characterization, and novel implications for subunit interactions. Biochemistry. 2000 Aug;39(30):9018-29.
Stevens K, Cirillo L, Zaret KS. Creating temperature-sensitive winged helix transcription factors. Amino acids that stabilize the DNA binding domain of HNF3. The Journal of biological chemistry. 2000 Sep 29;275(39):30471-7.
Taylor JC, Markham GD. The bifunctional active site of S-adenosylmethionine synthetase. Roles of the basic residues. The Journal of biological chemistry. 2000 Feb 11;275(6):4060-5.
Yi J, Arthur JW, Dunbrack RL, Skalka AM. An inhibitory monoclonal antibody binds at the turn of the helix-turn-helix motif in the N-terminal domain of HIV-1 integrase. The Journal of biological chemistry. 2000 Dec 08;275(49):38739-48.
Yi J, Asante-Appiah E, Skalka AM. Divalent cations stimulate preferential recognition of a viral DNA end by HIV-1 integrase. Biochemistry. 1999 Jun 29;38(26):8458-68.
The above publications are sorted by year, faculty last name, and first author. Click on any highlighted author listed to find all publications attributed to that individual. Click on the publication title to see the abstract. First authors who are faculty are highlighted like this. Last authors who are faculty are highlighted like this. Other authors who are faculty are highlighted like this.

MeSH cloud from publications including the MeSH term Site-Directed Mutagenesis

Site-Directed Mutagenesis genetics chemistry metabolism US Gov't Support-PHS Kinetics enzymology Non-US Gov't Support Molecular Models Molecular Sequence Data Binding Sites Recombinant Proteins Amino Acid Sequence Protein Binding Protein Conformation Tertiary Protein Structure Human Escherichia coli Porphobilinogen Synthase Mutation biosynthesis Amino Acid Substitution antagonists & inhibitors Cell Line physiology Hydrogen-Ion Concentration Substrate Specificity Apoptosis Phosphorylation Secondary Protein Structure Enzyme Activation Base Sequence Amino Acid Motifs pharmacology Divalent Cations Cysteine Magnesium HIV Integrase immunology Crystallization Transcription Factors Catalytic Domain Electron Spin Resonance Spectroscopy X-Ray Crystallography Viral DNA Post-Translational Protein Processing Cell Culture Biological Models Spin Labels Methionine Adenosyltransferase Circular Dichroism Manganese Nuclear Proteins Zinc Genetic Transcription S-Adenosylmethionine DNA-Binding Proteins Quaternary Protein Structure methods Mice Amino Acid Sequence Homology Signal Transduction Cell Survival Peptide Fragments Virus Replication Enzyme Inhibitors drug effects Cultured Tumor Cells cdc42 GTP-Binding Protein Catalysis HIV-1 Biomolecular Nuclear Magnetic Resonance Rats Cattle rho GTP-Binding Proteins Fibroblasts Recombinant Fusion Proteins Solvents Non-US Gov't Research Support Heptanoates Hydroxyl Radical Lead Conserved Sequence Mass Spectrometry-Matrix-Assisted Laser Desorption-Ionization src Homology Domains Antibody Binding Sites Cell Adhesion Proto-Oncogene Proteins c-bcl-2 US Gov't Research Support-PHS Molecular Evolution Escherichia coli Proteins Sprague-Dawley Rats Enzyme-Linked Immunosorbent Assay Gene Silencing Structure-Activity Relationship Mitogen-Activated Protein Kinases Oocytes Phosphoproteins cytology Cultured Cells Bacteriorhodopsins Protein Isoforms Microinjections Hydrophobic and Hydrophilic Interactions Xenopus Focal Adhesions Thermodynamics ge [Genetics] Cell Division Cell Cycle Proteins Protein Structural Homology Peas Viral RNA Immunologic Cytotoxicity Tests Schiff Bases Tryptophan ch [Chemistry] chemical synthesis Peptides Potassium Chloride Transfection Phosphotyrosine Myoglobin Mouse Mammary Tumor Virus Micrococcal Nuclease Motion Dominant Genes Chromatin Assembly and Disassembly Genetic Models Immunologic Cytotoxicity Quantum Theory Nucleosomes Virus Integration Fluorescence Microscopy Peptide Chain Termination Immunologic Receptors Vaccinia virus Nucleic Acid Conformation Bovine Viral Diarrhea Viruses Helix-Loop-Helix Motifs Natural Killer Cells Chromatin Synthetic Genes Sequence Deletion Viral Gene Expression Regulation Neurons Glucocorticoid Receptors Caspases Caenorhabditis elegans Protein-Tyrosine-Phosphatase
Last updated on Wednesday, February 05, 2020