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Publication Listing for the MeSH term Pyrazoles. Found 8 abstracts

Drilon A, Laetsch TW, Kummar S, DuBois SG, Lassen UN, Demetri GD, Nathenson M, Doebele RC, Farago AF, Pappo AS, Turpin B, Dowlati A, Brose MS, Mascarenhas L, Federman N, Berlin J, El-Deiry WS, Baik C, Deeken J, Boni V, Nagasubramanian R, Taylor M, Rudzinski ER, Meric-Bernstam F, Sohal DP, Ma PC, Raez LE, Hechtman JF, Benayed R, Ladanyi M, Tuch BB, Ebata K, Cruickshank S, Ku NC, Cox MC, Hawkins DS, Hong DS, Hyman DM. Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children. The New England journal of medicine. 2018 Feb 22;378(8):731-9.   PMCID: PMC5857389
Nieborowska-Skorska M, Maifrede S, Dasgupta Y, Sullivan K, Flis S, Le BV, Solecka M, Belyaeva EA, Kubovcakova L, Nawrocki M, Kirschner M, Zhao H, Prchal JT, Piwocka K, Moliterno AR, Wasik M, Koschmieder S, Green TR, Skoda RC, Skorski T. Ruxolitinib-induced defects in DNA repair cause sensitivity to PARP inhibitors in myeloproliferative neoplasms. Blood. 2017 Dec 28;130(26):2848-59.   PMCID: PMC5746670
Raje V, Derecka M, Cantwell M, Meier J, Szczepanek K, Sisler JD, Strobl B, Gamero A, Harris TE, Larner AC. Kinase Inactive Tyrosine Kinase (Tyk2) Supports Differentiation of Brown Fat Cells. Endocrinology. 2017 Jan;158(1):148-57.   PMCID: PMC5412977
Gritsina G, Xiao F, O'Brien SW, Gabbasov R, Maglaty MA, Xu RH, Thapa RJ, Zhou Y, Nicolas E, Litwin S, Balachandran S, Sigal LJ, Huszar D, Connolly DC. Targeted Blockade of JAK/STAT3 Signaling Inhibits Ovarian Carcinoma Growth. Mol Cancer Ther. 2015 Apr;14(4):1035-47.   PMCID: PMC4394029
Vijayvergia N, Mehra R. Clinical challenges in targeting anaplastic lymphoma kinase in advanced non-small cell lung cancer. Cancer Chemother Pharmacol. 2014 Sep;74(3):437-46.
Anastassiadis T, Duong-Ly KC, Deacon SW, Lafontant A, Ma H, Devarajan K, Dunbrack RL, Wu J, Peterson JR. A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-regulated kinase (ERK) inhibitor. The Journal of biological chemistry. 2013 Sep 27;288(39):28068-77.   PMCID: PMC3784719
Lubet RA, Clapper ML, McCormick DL, Pereira MA, Chang WC, Steele VE, Fischer SM, Juliana MM, Grubbs CJ. Chemopreventive efficacy of Targretin in rodent models of urinary bladder, colon/intestine, head and neck and mammary cancers. Oncol Rep. 2012 May;27(5):1400-6.
Ratushny V, Pathak HB, Beeharry N, Tikhmyanova N, Xiao F, Li T, Litwin S, Connolly DC, Yen TJ, Weiner LM, Godwin AK, Golemis EA. Dual inhibition of SRC and Aurora kinases induces postmitotic attachment defects and cell death. Oncogene. 2012 Mar 08;31(10):1217-27.   PMCID: PMC3204164
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MeSH cloud from publications including the MeSH term Pyrazoles

Pyrazoles Female metabolism pharmacology genetics drug effects drug therapy Pyrimidines Protein Kinase Inhibitors Male Antineoplastic Agents therapeutic use Mice Neoplasms antagonists & inhibitors Tumor Cell Line Animal Disease Models pathology Mutation Apoptosis chemistry Receptor Protein-Tyrosine Kinases Phosphorylation Cell Movement Piperazines Janus Kinase 2 Child Myogenic Regulatory Factor 5 prevention & control Pyridazines Cell Adhesion Young Adult Fusion Oncogene Proteins Adenosine Triphosphate Pyrroles Transgenic Mice DNA-Binding Proteins Sprague-Dawley Rats Non-Steroidal Anti-Inflammatory Agents cytology Cultured Cells Protein-Serine-Threonine Kinases Poly(ADP-ribose) Polymerase Inhibitors analysis Molecular Targeted Therapy Gene Expression Gene Expression Profiling Mitosis Cluster Analysis Matrix Metalloproteinases Drug Synergism Middle Aged methods MAP Kinase Signaling System CHO Cells Colonic Neoplasms Inbred C57BL Mice Head and Neck Neoplasms Phthalazines Urinary Bladder Neoplasms Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha Cell Survival Sulfonamides Myeloproliferative Disorders Analgesics Drug Design Calreticulin Heterografts Protein Kinases Adolescent Neoplasm Drug Resistance Xenograft Model Antitumor Assays Cultured Tumor Cells Kaplan-Meier Estimate Intestinal Neoplasms Ovarian Neoplasms Thiazoles Cricetulus Cyclooxygenase 2 Inhibitors Knockout Mice Tetrahydronaphthalenes src-Family Kinases Lung Neoplasms Janus Kinases diagnosis Anticarcinogenic Agents classification Protein Conformation TYK2 Kinase chemically induced Brown Adipocytes physiology Drug Dose-Response Relationship inhibitors Adult Central Nervous System Neoplasms Gene Expression Regulation Rats Thrombopoietin Receptors Disease-Free Survival Animal Mammary Neoplasms secondary Adipogenesis Signal Transduction Aged Inbred F344 Rats STAT3 Transcription Factor IGF Type 1 Receptor DNA Repair Preschool Child Cell Line Infant Pyridines Integrin alphaVbeta3 Insulin Receptor administration & dosage Transcription Factors Non-Small-Cell Lung Carcinoma antagonists & X-Ray Crystallography Cell Proliferation
Last updated on Friday, January 03, 2020