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Publication Listing for the MeSH term Pyrazines. Found 9 abstracts

Choueiri TK, Plimack E, Arkenau HT, Jonasch E, Heng DY, Powles T, Frigault MM, Clark EA, Handzel AA, Gardner H, Morgan S, Albiges L, Pal SK. Biomarker-Based Phase II Trial of Savolitinib in Patients With Advanced Papillary Renal Cell Cancer. J Clin Oncol. 2017 Sep 10;35(26):2993-3001.
Prudnikova TY, Chernoff J. The Group I Pak inhibitor Frax-1036 sensitizes 11q13-amplified ovarian cancer cells to the cytotoxic effects of Rottlerin. Small GTPases. 2017 Oct 02;8(4):193-8.   PMCID: PMC5680705
Chiang YT, Ip W, Shao W, Song ZE, Chernoff J, Jin T. Activation of cAMP signaling attenuates impaired hepatic glucose disposal in aged male p21-activated protein kinase-1 knockout mice. Endocrinology. 2014 Jun;155(6):2122-32.   PMCID: NO NIH funding
Evens AM, Smith MR, Lossos IS, Helenowski I, Millenson M, Winter JN, Rosen ST, Gordon LI. Frontline bortezomib and rituximab for the treatment of newly diagnosed high tumour burden indolent non-Hodgkin lymphoma: a multicentre phase II study. Br J Haematol. 2014 Aug;166(4):514-20.
Singh LR, Gupta S, Honig NH, Kraus JP, Kruger WD. Activation of mutant enzyme function in vivo by proteasome inhibitors and treatments that induce Hsp70. PLoS Genet. 2010 Jan;6(1):e1000807.   PMCID: PMC2795852
Ruggeri BA, Robinson C, Angeles T, Wilkinson Jt, Clapper ML. The chemopreventive agent oltipraz possesses potent antiangiogenic activity in vitro, ex vivo, and in vivo and inhibits tumor xenograft growth. Clin Cancer Res. 2002 Jan;8(1):267-74.
Szarka CE, Yao KS, Pfeiffer GR, Balshem AM, Litwin S, Frucht H, Goosenberg EB, Engstrom PF, Clapper ML, O'Dwyer PJ. Chronic dosing of oltipraz in people at increased risk for colorectal cancer. Cancer Detect Prev. 2001 Jan;25(4):352-61.
O'Dwyer PJ, Clayton M, Halbherr T, Myers CB, Yao K. Cellular kinetics of induction by oltipraz and its keto derivative of detoxication enzymes in human colon adenocarcinoma cells. Clin Cancer Res. 1997 May;3(5):783-91.
O'Dwyer PJ, Johnson SW, Khater C, Krueger A, Matsumoto Y, Hamilton TC, Yao KS. The chemopreventive agent oltipraz stimulates repair of damaged DNA. Cancer Res. 1997 Mar 15;57(6):1050-3.
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MeSH cloud from publications including the MeSH term Pyrazines

Pyrazines drug effects genetics Male drug therapy US Gov't Support-PHS Female metabolism Human Anticarcinogenic Agents Non-US Gov't Support pharmacology Aged pathology Cultured Tumor Cells administration & dosage 80 and over Aged Mice therapeutic use adverse effects Cultured Cells prevention & control Middle Aged Knockout Mice p21-Activated Kinases blood Glutathione Transferase enzymology NAD(P)H Dehydrogenase (Quinone) antagonists & inhibitors Adult Liver Signal Transduction Boronic Acids DNA Adducts Prospective Studies Glucose signal transduction Treatment Outcome biosynthesis Growth Factor Receptors Triazines Gene Expression methods Colonic Neoplasms Neoplastic Gene Expression Regulation Inbred C57BL Mice Adenocarcinoma Oral Administration Animal Cystathionine beta-Synthase Cell Division blood supply Cell Survival Renal Cell Carcinoma prognosis Kidney Neoplasms follicular lymphoma Insulin-Like Growth Factor I Heterologous Transplantation Proto-Oncogene Proteins c-met Colorectal Neoplasms Pyrimidines p21 inactivated kinase Pancreatic Ribonuclease Triazoles cancer Kaplan-Meier Estimate Rituximab Ovarian Neoplasms Neoplasm DNA Protein Kinase Inhibitors Receptor Protein-Tyrosine Kinases Antineoplastic Combined Chemotherapy Protocols Saccharomyces cerevisiae HSP70 Heat-Shock Proteins Monoclonal Antibodies-Murine-Derived Acetophenones Cell Cycle treatment ovarian cancer Mutation Human Chromosomes-Pair 11 Angiogenesis Inhibitors Enzyme Activation Genetic Transcription Drug Dose-Response Relationship protein kinase inhibitors Real-Time Polymerase Chain Reaction oncogene Proteasome Endopeptidase Complex Survival Analysis Pathologic Neovascularization Middle Age Drug Synergism Vascular Endothelium Rats toxicity Cisplatin pharmacokinetics Fibroblasts Vascular Endothelial Growth Factor Receptors Biological Tumor Markers Disease-Free Survival Benzopyrans Homocystinuria Enzyme Induction Drug Metabolic Detoxication DNA Repair Cell Line Glutathione Bortezomib mortality Fibroblast Growth Factor Receptors antagonists & Oligonucleotide Array Sequence Analysis Hepatocytes chromosomal amplification Kinetics sensitized screen Enzyme Inhibitors Tumor Biomarkers Piperidines DNA Damage Non-Hodgkin Lymphoma Colforsin deficiency Young Adult Tumor Cell Line Nude Mice Glucagon-Like Peptide 1 Messenger RNA Hemangiosarcoma Cyclic AMP
Last updated on Friday, August 14, 2020