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Publication Listing for the MeSH term Proto-Oncogene Proteins c-akt. Found 28 abstracts

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Zhao YZ, Zhang M, Wong HL, Tian XQ, Zheng L, Yu XC, Tian FR, Mao KL, Fan ZL, Chen PP, Li XK, Lu CT. Prevent diabetic cardiomyopathy in diabetic rats by combined therapy of aFGF-loaded nanoparticles and ultrasound-targeted microbubble destruction technique. J Control Release. 2016 Feb 10;223:11-21.
Badolia R, Manne BK, Dangelmaier C, Chernoff J, Kunapuli SP. Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets. Blood. 2015 Jan;125(1):175-84.   PMCID: PMC4281826
Conde-Perez A, Gros G, Longvert C, Pedersen M, Petit V, Aktary Z, Viros A, Gesbert F, Delmas V, Rambow F, Bastian BC, Campbell AD, Colombo S, Puig I, Bellacosa A, Sansom O, Marais R, Van Kempen LC, Larue L. A caveolin-dependent and PI3K/AKT-independent role of PTEN in beta-catenin transcriptional activity. Nat Commun. 2015 Jan;6:8093.   PMCID: PMC4560817
Sasano T, Mabuchi S, Kuroda H, Kawano M, Matsumoto Y, Takahashi R, Hisamatsu T, Sawada K, Hashimoto K, Isobe A, Testa JR, Kimura T. Preclinical efficacy for AKT targeting in clear cell carcinoma of the ovary. Molecular Cancer Research. 2015 Apr;13(4):795-806.   PMCID: PMC4398602
Brana I, Berger R, Golan T, Haluska P, Edenfield J, Fiorica J, Stephenson J, Martin LP, Westin S, Hanjani P, Jones MB, Almhanna K, Wenham RM, Sullivan DM, Dalton WS, Gunchenko A, Cheng JD, Siu LL, Gray JE. A parallel-arm phase I trial of the humanised anti-IGF-1R antibody dalotuzumab in combination with the AKT inhibitor MK-2206, the mTOR inhibitor ridaforolimus, or the NOTCH inhibitor MK-0752, in patients with advanced solid tumours. Br J Cancer. 2014 Nov 11;111(10):1932-44.   PMCID: Pmc4229637
Makhov P, Golovine K, Teper E, Kutikov A, Mehrazin R, Corcoran A, Tulin A, Uzzo RG, Kolenko VM. Piperlongumine promotes autophagy via inhibition of Akt/mTOR signalling and mediates cancer cell death. Br J Cancer. 2014 Feb 18;110(4):899-907.   PMCID: PMC3929888
Psyrri A, Lee JW, Pectasides E, Vassilakopoulou M, Kosmidis EK, Burtness BA, Rimm DL, Wanebo HJ, Forastiere AA. Prognostic biomarkers in phase II trial of cetuximab-containing induction and chemoradiation in resectable HNSCC: Eastern cooperative oncology group E2303. Clin Cancer Res. 2014 Jun;20(11):3023-32.   PMCID: Pmc4049169
Silver L, Michael JV, Goldfinger LE, Gallo G. Activation of PI3K and R-Ras signaling promotes the extension of sensory axons on inhibitory chondroitin sulfate proteoglycans. Dev Neurobiol. 2014 Sep;74(9):918-33.   PMCID: 4235675
Cheung M, Testa JR. Diverse mechanisms of AKT pathway activation in human malignancy. Curr Cancer Drug Targets. 2013 Mar;13(3):234-44.   PMCID: PMC3678724
Arias-Romero LE, Villamar-Cruz O, Pacheco A, Kosoff R, Huang M, Muthuswamy SK, Chernoff J. A Rac-Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells. Oncogene. 2010 Oct 28;29(43):5839-49.   PMCID: PMC2965784
Tan Y, You H, Wu C, Altomare DA, Testa JR. Appl1 is dispensable for mouse development, and loss of Appl1 has growth factor-selective effects on Akt signaling in murine embryonic fibroblasts. The Journal of biological chemistry. 2010 Feb 26;285(9):6377-89.   PMCID: PMC2825433
Xu J, Testa JR. DLX5 (distal-less homeobox 5) promotes tumor cell proliferation by transcriptionally regulating MYC. The Journal of biological chemistry. 2009 Jul 31;284(31):20593-601.   PMCID: PMC2742824
MacFarlane AW, Yamazaki T, Fang M, Sigal LJ, Kurosaki T, Campbell KS. Enhanced NK-cell development and function in BCAP-deficient mice. Blood. 2008 Jul;112(1):131-40.
Patel BB, He YA, Li XM, Frolov A, Vanderveer L, Slater C, Schilder RJ, von Mehren M, Godwin AK, Yeung AT. Molecular mechanisms of action of imatinib mesylate in human ovarian cancer: a proteomic analysis. Cancer Genomics Proteomics. 2008 May;5(3-4):137-49.
Serebriiskii I, Castello-Cros R, Lamb A, Golemis EA, Cukierman E. Fibroblast-derived 3D matrix differentially regulates the growth and drug-responsiveness of human cancer cells. Matrix biology : journal of the International Society for Matrix Biology. 2008 Jul;27(6):573-85.   PMCID: PMC2603546
Tarn C, Rink L, Merkel E, Flieder D, Pathak H, Koumbi D, Testa JR, Eisenberg B, von Mehren M, Godwin AK. Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors. Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8387-92.   PMCID: PMC2448846
Ariazi EA, Kraus RJ, Farrell ML, Jordan VC, Mertz JE. Estrogen-related receptor alpha1 transcriptional activities are regulated in part via the ErbB2/HER2 signaling pathway. Molecular cancer research : MCR. 2007 Jan;5(1):71-85.
Kim SH, Nakagawa H, Navaraj A, Naomoto Y, Klein-Szanto AJ, Rustgi AK, El-Deiry WS. Tumorigenic conversion of primary human esophageal epithelial cells using oncogene combinations in the absence of exogenous Ras. Cancer Res. 2006 Nov;66(21):10415-24.
Bellacosa A, Kumar CC, Di Cristofano A, Testa JR. Activation of AKT kinases in cancer: implications for therapeutic targeting. Advances in cancer research. 2005 Jan;94:29-86.
Bellacosa A, Testa JR, Moore R, Larue L. A portrait of AKT kinases: human cancer and animal models depict a family with strong individualities. Cancer Biol Ther. 2004 Mar;3(3):268-75.
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MeSH cloud from publications including the MeSH term Proto-Oncogene Proteins c-akt

Proto-Oncogene Proteins c-akt metabolism Signal Transduction Mice genetics pharmacology physiology Female drug effects Tumor Cell Line drug therapy pathology Cell Proliferation Male Neoplasms Apoptosis therapeutic use cytology Antineoplastic Agents Phosphorylation Prognosis Mitogen-Activated Protein Kinase Kinases Phosphatidylinositol 3-Kinases Neoplastic Gene Expression Regulation TOR Serine-Threonine Kinases Breast Neoplasms Cell Survival enzymology Xenograft Model Antitumor Assays Neoplastic Cell Transformation antagonists & inhibitors administration & dosage NIH 3T3 Cells ras Proteins Gene Expression Profiling therapy Western Blotting Adult Tissue Array Analysis Middle Aged erbB-2 Receptor Ovarian Neoplasms Fibroblasts Epidermal Growth Factor Receptor physiopathology Fluorescent Antibody Technique Gel Electrophoresis-Two-Dimensional IGF Type 1 Receptor Multiprotein Complexes Cell Culture Techniques Transgenic Mice analogs & derivatives Cultured Tumor Cells Immunohistochemistry Neoplasm Drug Resistance Piperazines Neoplasm Transplantation Proto-Oncogene Proteins Knockout Mice Antineoplastic Combined Chemotherapy Protocols Biological Tumor Markers Protein-Serine-Threonine Kinases 1-Phosphatidylinositol 3-Kinase analysis Aged Genetic Transcription Platelet-Derived Growth Factor alpha Receptor Enzyme Activation Pyrimidines Esophageal Neoplasms Embryonic Development Aneuploidy SCID Mice Up-Regulation Lymphoma Lung Neoplasms ras Genes Clear Cell Adenocarcinoma Melanocytes Chloroquine Mutation Signal Transducing Adaptor Proteins Melanoma Skin Neoplasms Coronary Circulation Chemoradiotherapy Gene Amplification Cell Enlargement Reactive Oxygen Species CD29 Antigens Homeodomain Proteins Electrophoretic Mobility Shift Assay Congenic Mice Small Interfering RNA Cisplatin 80 and over Aged Lymphocyte Specific Protein Tyrosine Kinase p56(lck) Transcriptional Activation NF-kappa B Glycogen Synthase Kinase 3 Preventive strategy mortality Presenilin-2 Cell Aging Proportional Hazards Models neurite Animal Disease Models Akt Propionates beta Catenin deficiency Oncogenes Prostatic Neoplasms bcl-X Protein Carrier Proteins Biological Models Follow-Up Studies Pyrroles Randomized Controlled Trials as Topic Progesterone Receptors Paclitaxel Sprague-Dawley Rats Myocardium Ultrasound-targeted microbubble destruction technique etiology Autophagy Nanoparticles Protein Transport Gene Silencing biosynthesis Cultured Cells Phosphatidylinositol Phosphates adverse Transformed Cell Line myc Genes Spinal Ganglia regeneration Phase III Clinical Trials as Topic Microbubbles HEK293 Cells Nuclear Receptor Coactivator 2 Tissue Scaffolds effects Kidney Neoplasms Heterologous Transplantation Gastrointestinal Stromal Tumors Sulfones Mass Spectrometry DNA Mutational Analysis immunology
Last updated on Saturday, August 15, 2020