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Publication Listing for the MeSH term Protein-Serine-Threonine Kinases. Found 54 abstracts

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Leclerc D, Pham DN, Levesque N, Truongcao M, Foulkes WD, Sapienza C, Rozen R. Oncogenic role of PDK4 in human colon cancer cells. Br J Cancer. 2017 Mar 28;116(7):930-6.   PMCID: PMC5379150
Liu H, Sun Q, Sun Y, Zhang J, Yuan H, Pang S, Qi X, Wang H, Zhang M, Zhang H, Yu C, Gu C. MELK and EZH2 Cooperate to Regulate Medulloblastoma Cancer Stem-like Cell Proliferation and Differentiation. Molecular cancer research : MCR. 2017 Sep;15(9):1275-86.
Ji W, Arnst C, Tipton AR, Bekier ME, Taylor WR, Yen TJ, Liu ST. OTSSP167 Abrogates Mitotic Checkpoint through Inhibiting Multiple Mitotic Kinases. PLoS One. 2016 Jan;11(4):e0153518.   PMCID: PMC4833387
Ji W, Arnst C, Tipton AR, Bekier ME, Taylor WR, Yen TJ, Liu ST. OTSSP167 Abrogates Mitotic Checkpoint through Inhibiting Multiple Mitotic Kinases. PLoS One. 2016 Jan;11(4):e0153518.   PMCID: PMC4833387
Xu Q, Malecka KL, Fink L, Jordan EJ, Duffy E, Kolander S, Peterson JR, Dunbrack RL. Identifying three-dimensional structures of autophosphorylation complexes in crystals of protein kinases. Science signaling. 2015 Dec;8(405):rs13.   PMCID: 4766099
Thomas CJ, Kotova E, Andrake M, Adolf-Bryfogle J, Glaser R, Regnard C, Tulin AV. Kinase-mediated changes in nucleosome conformation trigger chromatin decondensation via poly(ADP-ribosyl)ation. Molecular cell. 2014 Mar 06;53(5):831-42.   PMCID: PMC3951681
Morishita A, Zaidi MR, Mitoro A, Sankarasharma D, Szabolcs M, Okada Y, D'Armiento J, Chada K. HMGA2 is a driver of tumor metastasis. Cancer research. 2013 Jul 15;73(14):4289-99.   PMCID: Pmc3715567
Plotnikova OV, Nikonova AS, Loskutov YV, Kozyulina PY, Pugacheva EN, Golemis EA. Calmodulin activation of Aurora-A kinase (AURKA) is required during ciliary disassembly and in mitosis. Mol Biol Cell. 2012 Jul;23(14):2658-70.   PMCID: PMC3395655
Ratushny V, Pathak HB, Beeharry N, Tikhmyanova N, Xiao F, Li T, Litwin S, Connolly DC, Yen TJ, Weiner LM, Godwin AK, Golemis EA. Dual inhibition of SRC and Aurora kinases induces postmitotic attachment defects and cell death. Oncogene. 2012 Mar 08;31(10):1217-27.   PMCID: PMC3204164
Dees EC, Infante JR, Cohen RB, O'Neil BH, Jones S, von Mehren M, Danaee H, Lee Y, Ecsedy J, Manfredi M, Galvin K, Stringer B, Liu H, Eton O, Fingert H, Burris H. Phase 1 study of MLN8054, a selective inhibitor of Aurora A kinase in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2011 Apr;67(4):945-54.   PMCID: PMC3026871
Astsaturov I, Ratushny V, Sukhanova A, Einarson MB, Bagnyukova T, Zhou Y, Devarajan K, Silverman JS, Tikhmyanova N, Skobeleva N, Pecherskaya A, Nasto RE, Sharma C, Jablonski SA, Serebriiskii IG, Weiner LM, Golemis EA. Synthetic lethal screen of an EGFR-centered network to improve targeted therapies. Science signaling. 2010 Jan;3(140):ra67.   PMCID: PMC2950064
Beeharry N, Yen TJ. p53-dependent apoptosis in response to spindle damage is linked to loss of Bub1. Cancer Biol Ther. 2009 Apr;8(7):645-7.
Huang H, Yen TJ. BubR1 is an effector of multiple mitotic kinases that specifies kinetochore: microtubule attachments and checkpoint. Cell cycle (Georgetown, Tex). 2009 Apr 15;8(8):1164-7.
Huang H, Hittle J, Zappacosta F, Annan RS, Hershko A, Yen TJ. Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit. The Journal of cell biology. 2008 Nov 17;183(4):667-80.   PMCID: PMC2582891
Pugacheva EN, Jablonski SA, Hartman TR, Henske EP, Golemis EA. HEF1-dependent Aurora A activation induces disassembly of the primary cilium.[see comment]. Cell. 2007 Jun 29;129(7):1351-63.
Rennefahrt UE, Deacon SW, Parker SA, Devarajan K, Beeser A, Chernoff J, Knapp S, Turk BE, Peterson JR. Specificity profiling of Pak kinases allows identification of novel phosphorylation sites. The Journal of biological chemistry. 2007 May 25;282(21):15667-78.
Beeser A, Chernoff J. Production and use of a cell permeable inhibitor of group A Paks (TAT-PID) to analyze signal transduction. Methods (San Diego, Calif). 2005 Oct;37(2):203-7.
Bellacosa A, Kumar CC, Di Cristofano A, Testa JR. Activation of AKT kinases in cancer: implications for therapeutic targeting. Advances in cancer research. 2005 Jan;94:29-86.
Altomare DA, Wang HQ, Skele KL, De Rienzo A, Klein-Szanto AJ, Godwin AK, Testa JR. AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth. Oncogene. 2004 Jul 29;23(34):5853-7.
Bellacosa A, Testa JR, Moore R, Larue L. A portrait of AKT kinases: human cancer and animal models depict a family with strong individualities. Cancer Biol Ther. 2004 Mar;3(3):268-75.
The above publications are sorted by year, faculty last name, and first author. Click on any highlighted author listed to find all publications attributed to that individual. Click on the publication title to see the abstract. First authors who are faculty are highlighted like this. Last authors who are faculty are highlighted like this. Other authors who are faculty are highlighted like this.

MeSH cloud from publications including the MeSH term Protein-Serine-Threonine Kinases

Protein-Serine-Threonine Kinases genetics metabolism physiology Signal Transduction Phosphorylation pharmacology Female Mitosis antagonists & inhibitors Proto-Oncogene Proteins Apoptosis Kinetochores pathology Neoplasms Protein Kinase Inhibitors Small Interfering RNA chemistry Male inhibitors drug effects Cultured Tumor Cells Naphthyridines Tumor Cell Line Cell Cycle Proteins Cell Proliferation Mice MCF-7 Cells Cell Line immunology ai [Antagonists & Inhibitors] EC 2-7-1-37 (Protein-Serine-Threonine Kinases) Enzyme Activation 0 (Enzyme Inhibitors) Cilia me [Metabolism] Cell Movement Microtubules drug therapy Protein Kinases Tertiary Protein Structure enzymology Middle Aged Molecular Models HCT116 Cells biosynthesis methods Phosphoproteins Histone Deacetylases cdc42 GTP-Binding Protein Enzyme Inhibitors HeLa Cells RNA Interference Antibodies antagonists & pd [Pharmacology] Aurora Kinase B Centromere M Phase Cell Cycle Checkpoints Antineoplastic Agents Proto-Oncogene Proteins c-akt Signal Transducing Adaptor Proteins de [Drug Effects] Indirect Fluorescent Antibody Technique Adult Real-Time Polymerase Chain Reaction Protein Kinase C Cell Enlargement Cytokinesis Cytotoxins rho GTP-Binding Proteins Cisplatin 80 and over Aged Recombinant Fusion Proteins Carcinogenesis Open Reading Frames Calmodulin Peptide Fragments Amino Acid Motifs COS Cells Preschool Child EC 2-7-1-137 (1-Phosphatidylinositol 3-Kinase) Poly(ADP-ribose) Polymerases 0 (Chromones) Aurora Kinases Poly Adenosine Diphosphate Ribose Immunohistochemistry Site-Directed Mutagenesis Enhancer of Zeste Homolog 2 Protein Half-Life Tumor Biomarkers deficiency Cell Adhesion Young Adult Macrophage Colony-Stimulating Factor Receptor tat Gene Products Follow-Up Studies Pyrroles Histones Medulloblastoma Disorders of Excessive Somnolence therapy Protein Databases EC 2-7-1-37 (Protein Kinases) 0 (Morpholines) Structure-Activity Relationship 0 (Phosphoproteins) EC 3-5-1 (Histone Deacetylases) adverse Epidermal Growth Factor Receptor physiopathology Xenopus ul [Ultrastructure] Colonic Neoplasms US Gov't Support-PHS Oral Administration HEK293 Cells Cell Division ge [Genetics] Cell Survival effects Protein Structural Homology Human Heterografts EC 2-7-1-37 (proto-oncogene protein akt) Prognosis Adolescent Neoplasm Drug Resistance Case-Control Studies p56(lck) Thiazoles Protein Interaction Mapping Benzazepines DNA Methylphenidate Drug Discovery Cell Cycle 53123-88-9 (Sirolimus) Anaphase Micrococcal Nuclease Non-US Gov't Support Protein Conformation Pyrazoles Drosophila Proteins chemically induced Hela Cells Morpholines Protein Binding Nucleosomes Drug Dose-Response Relationship
Last updated on Wednesday, August 05, 2020