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Publication Listing for the MeSH term Inhibitory Concentration 50. Found 7 abstracts

Huang F, Goyal N, Sullivan K, Hanamshet K, Patel M, Mazina OM, Wang CX, An WF, Spoonamore J, Metkar S, Emmitte KA, Cocklin S, Skorski T, Mazin AV. Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitors. Nucleic acids research. 2016 May 19;44(9):4189-99.   PMCID: PMC4872086
Chandramouly G, McDevitt S, Sullivan K, Kent T, Luz A, Glickman JF, Andrake M, Skorski T, Pomerantz RT. Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers. Chem Biol. 2015 Nov 19;22(11):1491-504.   PMCID: PMC4701204
Gianti E, Carnevale V, DeGrado WF, Klein ML, Fiorin G. Hydrogen-bonded water molecules in the M2 channel of the influenza A virus guide the binding preferences of ammonium-based inhibitors. J Phys Chem B. 2015 Jan 22;119(3):1173-83.   PMCID: PMC4386636
Takahashi N, Li W, Banerjee D, Guan Y, Wada-Takahashi Y, Brennan MF, Chou TC, Scotto KW, Bertino JR. Sequence-dependent synergistic cytotoxicity of ET-743 and paclitaxel in human breast cancer cell lines in vitro and in vivo. Cancer Res. 2002 Dec;62(23):6909-15.
Piazza GA, Thompson WJ, Pamukcu R, Alila HW, Whitehead CM, Liu L, Fetter JR, Gresh WE, Klein-Szanto AJ, Farnell DR, Eto I, Grubbs CJ. Exisulind, a novel proapoptotic drug, inhibits rat urinary bladder tumorigenesis. Cancer Res. 2001 May 15;61(10):3961-8.
Takahashi N, Li WW, Banerjee D, Scotto KW, Bertino JR. Sequence-dependent enhancement of cytotoxicity produced by ecteinascidin 743 (ET-743) with doxorubicin or paclitaxel in soft tissue sarcoma cells. Clin Cancer Res. 2001 Oct;7(10):3251-7.
Rosario LA, O'Brien ML, Henderson CJ, Wolf CR, Tew KD. Cellular response to a glutathione S-transferase P1-1 activated prodrug. Mol Pharmacol. 2000 Jul;58(1):167-74.
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MeSH cloud from publications including the MeSH term Inhibitory Concentration 50

metabolism Inhibitory Concentration 50 pharmacology drug effects Human Cultured Tumor Cells Apoptosis Non-US Gov't Support Fluorescence Microscopy antagonists & inhibitors chemistry genetics US Gov't Support-PHS analogs & derivatives Animal pathology Antineoplastic Agents BRCA2 Protein inhibitors BRCA1 Protein Drug Synergism Protein Binding Rad52 DNA Repair and Recombination Protein Antitumor Drug Screening Assays antagonists & Dioxoles Cisplatin Cell Division biosynthesis Isoquinolines drug therapy Doxorubicin DNA Damage Female Paclitaxel Mice 5'-Cyclic-GMP Phosphodiesterase 3' Dihydroxyphenylalanine Cyclic GMP 3T3 Cells Hydrophobic and Hydrophilic Interactions Prodrugs Isoenzymes Mitosis HL-60 Cells Gene Knockdown Techniques Neoplasms Viral Matrix Proteins Allosteric Regulation Thermodynamics single-strand annealing Sulindac Cell Survival 5'-Cyclic-Nucleotide Phosphodiesterase 3' Glutathione Transferase genome instability Permeability RNA Interference Single-Stranded DNA Recombinant Proteins Fluorouracil Xenograft Model Antitumor Assays cancer therapeutics cancer homologous recombination Antineoplastic Combined Chemotherapy Protocols Alkylating Antineoplastic Agents Molecular Dynamics Simulation Flow Cytometry High-Throughput Screening Assays Cyclic GMP-Dependent Protein Kinases Anticarcinogenic Agents Mutation Protein Conformation chemically induced Rats Camptothecin Electrophoretic Mobility Shift Assay pharmacokinetics Cytotoxins Hydrogen Bonding Small Interfering RNA toxicity Breast Neoplasms Inbred F344 Rats DNA repair Cell Line Small Molecule Libraries Glutathione P-Glycoprotein administration & dosage Cell Proliferation Bladder Neoplasms Influenza A virus prevention & control isolation & purification Substrate Specificity Water deficiency Sarcoma Tumor Cell Line Nude Mice high-throughput screening Trimetrexate Drug Administration Schedule Cyclic AMP Enzyme Activation Drug Dose-Response Relationship Ammonium Compounds synthetic lethality
Last updated on Wednesday, August 05, 2020