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Publication Listing for the MeSH term IGF Type 1 Receptor. Found 8 abstracts

Bassi DE, Cenna J, Zhang J, Cukierman E, Klein-Szanto AJ. Enhanced aggressiveness of benzopyrene-induced squamous carcinomas in transgenic mice overexpressing the proprotein convertase PACE4 (PCSK6). Mol Carcinog. 2015 Oct;54(10):1122-31.   PMCID: PMC4240754
Brana I, Berger R, Golan T, Haluska P, Edenfield J, Fiorica J, Stephenson J, Martin LP, Westin S, Hanjani P, Jones MB, Almhanna K, Wenham RM, Sullivan DM, Dalton WS, Gunchenko A, Cheng JD, Siu LL, Gray JE. A parallel-arm phase I trial of the humanised anti-IGF-1R antibody dalotuzumab in combination with the AKT inhibitor MK-2206, the mTOR inhibitor ridaforolimus, or the NOTCH inhibitor MK-0752, in patients with advanced solid tumours. Br J Cancer. 2014 Nov 11;111(10):1932-44.   PMCID: Pmc4229637
von Mehren M, Britten CD, Pieslor P, Saville W, Vassos A, Harris S, Galluppi GR, Darif M, Wainberg ZA, Cohen RB, Leong S. A phase 1, open-label, dose-escalation study of BIIB022 (anti-IGF-1R monoclonal antibody) in subjects with relapsed or refractory solid tumors. Invest New Drugs. 2014 Jun;32(3):518-25.   PMCID: Pmc4045341
Anastassiadis T, Duong-Ly KC, Deacon SW, Lafontant A, Ma H, Devarajan K, Dunbrack RL, Wu J, Peterson JR. A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-regulated kinase (ERK) inhibitor. The Journal of biological chemistry. 2013 Sep 27;288(39):28068-77.   PMCID: PMC3784719
Fu J, Bassi DE, Zhang J, Li T, Nicolas E, Klein-Szanto AJ. Transgenic overexpression of the proprotein convertase furin enhances skin tumor growth. Neoplasia (New York, NY). 2012 Apr;14(4):271-82.   PMCID: PMC3349254
Tarn C, Rink L, Merkel E, Flieder D, Pathak H, Koumbi D, Testa JR, Eisenberg B, von Mehren M, Godwin AK. Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors. Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8387-92.   PMCID: PMC2448846
Mercapide J, Lopez De Cicco R, Bassi DE, Castresana JS, Thomas G, Klein-Szanto AJ. Inhibition of Furin-mediated Processing Results in Suppression of Astrocytoma Cell Growth and Invasiveness. Clin Cancer Res. 2002 Jun;8(6):1740-6.
Tanno S, Mitsuuchi Y, Altomare DA, Xiao GH, Testa JR. AKT activation up-regulates insulin-like growth factor I receptor expression and promotes invasiveness of human pancreatic cancer cells. Cancer Res. 2001 Jan 15;61(2):589-93.
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MeSH cloud from publications including the MeSH term IGF Type 1 Receptor

IGF Type 1 Receptor metabolism pathology genetics antagonists & inhibitors Female Western Blotting drug therapy Mice Monoclonal Antibodies Adult Tumor Cell Line Human pharmacology Transfection Middle Aged drug effects Cell Proliferation pharmacokinetics Neoplasm Invasiveness Mutation Transgenic Mice Non-US Gov't Support Cultured Tumor Cells therapeutic use Neoplasms Proto-Oncogene Proteins c-akt Antineoplastic Agents US Gov't Support-PHS Aged Squamous Cell Carcinoma Male Skin Neoplasms squamous cell carcinoma therapy Reverse Transcriptase Polymerase Chain Reaction analogs & derivatives Gene Silencing Trachea Proto-Oncogene Proteins c-kit adverse Phosphorylation Sirolimus Brain Neoplasms Neoplastic Gene Expression Regulation TOR Serine-Threonine Kinases Phase III Clinical Trials as Topic Animal 3-Ring Heterocyclic Compounds Cell Division effects Drug Design Gastrointestinal Stromal Tumors Cohort Studies Sulfones Down-Regulation Benzopyrenes Pyrimidines Prognosis Neoplasm Drug Resistance DNA Mutational Analysis Apoptosis Protein Kinase Inhibitors Cricetulus Neoplasm Transplantation Pcsk6 immunology SCID Mice tumor progression Antineoplastic Combined Chemotherapy Protocols Precipitin Tests Furin Proto-Oncogene Proteins src-Family Kinases Up-Regulation In Vitro Recombinant DNA classification Protein Conformation Pyrazoles Platelet-Derived Growth Factor alpha Receptor chemically induced Enzyme Activation enzymology proprotein convertases physiology Immunoenzyme Techniques Maximum Tolerated Dose Drug Dose-Response Relationship Real-Time Polymerase Chain Reaction Gene Expression Regulation Astrocytoma Gene Amplification Proprotein Convertases Extracellular Matrix Transforming Growth Factor beta MAP Kinase Signaling System CHO Cells Rats blood Disease Progression bezo(a)pyrene Small Interfering RNA 80 and over Aged skin carcinogenesis Phosphoric Monoester Hydrolases Carcinogenesis Subcutaneous Injections chemistry Metalloendopeptidases Biological Tumor Markers Pace4 Notch Receptors Signal Transduction Keratinocytes Local Neoplasm Recurrence Mitogen-Activated Protein Kinase Kinases Cell Line Neoplasm Staging Phase II Clinical Trials as Topic Epidermis Insulin Receptor administration & dosage X-Ray Crystallography Tissue Distribution Immunohistochemistry Carcinogens Piperazines Pancreatic Neoplasms Propionates Pyridazines Benzene Derivatives Adenosine Triphosphate Plasmids Follow-Up Studies Pyrroles Randomized Controlled Trials as Topic alpha 1-Antitrypsin Subtilisins
Last updated on Wednesday, February 05, 2020