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Publication Listing for the MeSH term HIV Integrase. Found 14 abstracts

Koneru PC, Francis AC, Deng N, Rebensburg SV, Hoyte AC, Lindenberger J, Adu-Ampratwum D, Larue RC, Wempe MF, Engelman AN, Lyumkis D, Fuchs JR, Levy RM, Melikyan GB, Kvaratskhelia M. HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors. eLife. 2019 May 23;8.   PMCID: PMC6581505
Xia J, Flynn W, Levy RM. Improving Prediction Accuracy of Binding Free Energies and Poses of HIV Integrase Complexes Using the Binding Energy Distribution Analysis Method with Flattening Potentials. Journal of chemical information and modeling. 2018 Jul 23;58(7):1356-71.   PMCID: PMC6287956
Deng N, Hoyte A, Mansour YE, Mohamed MS, Fuchs JR, Engelman AN, Kvaratskhelia M, Levy R. Allosteric HIV-1 integrase inhibitors promote aberrant protein multimerization by directly mediating inter-subunit interactions: Structural and thermodynamic modeling studies. Protein science : a publication of the Protein Society. 2016 Nov;25(11):1911-7.   PMCID: PMC5079246
Patel D, Antwi J, Koneru PC, Serrao E, Forli S, Kessl JJ, Feng L, Deng N, Levy RM, Fuchs JR, Olson AJ, Engelman AN, Bauman JD, Kvaratskhelia M, Arnold E. A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain. The Journal of biological chemistry. 2016 Nov 04;291(45):23569-77.   PMCID: PMC5095411
Wickstrom L, Deng N, He P, Mentes A, Nguyen C, Gilson MK, Kurtzman T, Gallicchio E, Levy RM. Parameterization of an effective potential for protein-ligand binding from host-guest affinity data. Journal of molecular recognition : JMR. 2016 Jan;29(1):10-21.   PMCID: PMC4715590
Merkel G, Andrake MD, Ramcharan J, Skalka AM. Oligonucleotide-based assays for integrase activity. Methods (San Diego, Calif). 2009 Apr;47(4):243-8.   PMCID: PMC2743288
Ramcharan J, Colleluori DM, Merkel G, Andrake MD, Skalka AM. Mode of inhibition of HIV-I integrase by a C-terminal domain-specific monoclonal antibody. RETROVIROLOGY . 2006 Jan;3:34.
Taganov KD, Cuesta I, Daniel R, Cirillo LA, Katz RA, Zaret KS, Skalka AM. Integrase-specific enhancement and suppression of retroviral DNA integration by compacted chromatin structure in vitro. Journal of Virology. 2004 Jun;78(11):5848-55.
Yi J, Cheng H, Andrake MD, Dunbrack RL, Roder H, Skalka AM. Mapping the epitope of an inhibitory monoclonal antibody to the C-terminal DNA-binding domain of HIV-1 integrase. The Journal of biological chemistry. 2002 Apr 05;277(14):12164-74.
Yi J, Arthur JW, Dunbrack RL, Skalka AM. An inhibitory monoclonal antibody binds at the turn of the helix-turn-helix motif in the N-terminal domain of HIV-1 integrase. The Journal of biological chemistry. 2000 Dec 08;275(49):38739-48.
Yi J, Skalka AM. Mapping epitopes of monoclonal antibodies against HIV-1 integrase with limited proteolysis and matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Biopolymers. 2000 Jan;55(4):308-18.
Asante-Appiah E, Skalka AM. HIV-1 integrase: structural organization, conformational changes, and catalysis. Adv Virus Res. 1999 Jan;52:351-69.
Yi J, Asante-Appiah E, Skalka AM. Divalent cations stimulate preferential recognition of a viral DNA end by HIV-1 integrase. Biochemistry. 1999 Jun 29;38(26):8458-68.
Kukolj G, Jones KS, Skalka AM. Subcellular localization of avian sarcoma virus and human immunodeficiency virus type 1 integrases. J Virol. 1997 Jan;71(1):843-7.
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MeSH cloud from publications including the MeSH term HIV Integrase

HIV Integrase chemistry metabolism HIV-1 Molecular Models Non-US Gov't Support enzymology US Gov't Support-PHS genetics Protein Binding immunology Molecular Sequence Data Monoclonal Antibodies HIV Integrase Inhibitors Mass Spectrometry-Matrix-Assisted Laser Desorption-Ionization Amino Acid Substitution Allosteric Regulation Protein Conformation Amino Acid Sequence Catalytic Domain Human Enzyme-Linked Immunosorbent Assay Binding Sites pharmacology Kinetics Animal integrase Epitope Mapping HIV-1 integrase Ligands Thermodynamics Site-Directed Mutagenesis Structure-Activity Relationship Avian Sarcoma Viruses Viral DNA Catalysis Surface Plasmon Resonance drug effects Alanine Epitopes Protein Multimerization HEK293 Cells Base Sequence physiology DNA-Binding Proteins Endopeptidases HIV Protease me [Metabolism] allosteric inhibitors HIV Infections virology virus Protein Domains Recombinant Proteins ROC Curve Peptide Mapping human immunodeficiency virus (HIV) force field ch [Chemistry] medicinal chemistry allosteric HIV-1 integrase inhibitor Chemical Models Potassium Chloride Drug Discovery Helix-Turn-Helix Motifs vi [Virology] Cytoplasm Transfection Molecular Dynamics Simulation declared HeLa Cells Mutation Antibody Affinity Nuclear Proteins Subcellular Fractions Cysteine Enzyme Activation Retroviridae Molecular Docking Simulation Nucleosomes Chemical Databases Virus Integration Protein Sorting Signals HIV Antibodies protein-ligand binding Divalent Cations allosteric inhibitor drug discovery Thiophenes infectious disease Integrases beta-Galactosidase Area Under Curve Recombinant Fusion Proteins fragment screening Bedam microbiology Peptide Fragments Magnetic Resonance Spectroscopy Metals Integrase beta-Cyclodextrins Muramidase Chromatin Magnesium COS Cells drug therapy Opls Polyacrylamide Gel Electrophoresis Secondary Protein Structure Pyridines ph [Physiology] Isoleucine Carboxylic Acids antagonists & inhibitors Transcription Factors Tertiary Protein Structure X-ray crystallography hiv-1 X-Ray Crystallography Oligonucleotide Array Sequence Analysis Antiviral Agents Xylenes drug screening Molecular Conformation Antibody Binding Sites Substrate Specificity Manganese en [Enzymology] Plasmids Antibody Specificity Time Factors Computer Simulation Gist Hiv-1 Stereoisomerism HIV Antigens protein-protein docking methods free energy Cross-Linking Reagents ge [Genetics]
Last updated on Thursday, April 02, 2020