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Publication Listing for the MeSH term Enzyme Activation. Found 44 abstracts

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Lu H, Liu S, Zhang G, Bin W, Zhu Y, Frederick DT, Hu Y, Zhong W, Randell S, Sadek N, Zhang W, Chen G, Cheng C, Zeng J, Wu LW, Zhang J, Liu X, Xu W, Krepler C, Sproesser K, Xiao M, Miao B, Liu J, Song CD, Liu JY, Karakousis GC, Schuchter LM, Lu Y, Mills G, Cong Y, Chernoff J, Guo J, Boland GM, Sullivan RJ, Wei Z, Field J, Amaravadi RK, Flaherty KT, Herlyn M, Xu X, Guo W. PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas. Nature. 2017 Oct 05;550(7674):133-6.   PMCID: PMC5891348
Taniguchi K, Wu LW, Grivennikov SI, de Jong PR, Lian I, Yu FX, Wang K, Ho SB, Boland BS, Chang JT, Sandborn WJ, Hardiman G, Raz E, Maehara Y, Yoshimura A, Zucman-Rossi J, Guan KL, Karin M. A gp130-Src-YAP module links inflammation to epithelial regeneration. Nature. 2015 Mar 05;519(7541):57-62.   PMCID: 4447318
McCullough SD, Duncan KE, Swanton SM, Dailey LA, Diaz-Sanchez D, Devlin RB. Ozone induces a proinflammatory response in primary human bronchial epithelial cells through mitogen-activated protein kinase activation without nuclear factor-kappaB activation. Am J Respir Cell Mol Biol. 2014 Sep;51(3):426-35.
Cheung M, Testa JR. Diverse mechanisms of AKT pathway activation in human malignancy. Curr Cancer Drug Targets. 2013 Mar;13(3):234-44.   PMCID: PMC3678724
Itakura A, Aslan JE, Kusanto BT, Phillips KG, Porter JE, Newton PK, Nan XL, Insall RH, Chernoff J, McCarty OJ. p21-Activated Kinase (PAK) Regulates Cytoskeletal Reorganization and Directional Migration in Human Neutrophils. Plos One. 2013 Sep;8(9):e73063.   PMCID: PMC 3760889
Pacheco A, Chernoff J. Group I p21-activated kinases: emerging roles in immune function and viral pathogenesis. Int J Biochem Cell Biol. 2010 Jan;42(1):13-6.   PMCID: PMC2787825
Singh LR, Gupta S, Honig NH, Kraus JP, Kruger WD. Activation of mutant enzyme function in vivo by proteasome inhibitors and treatments that induce Hsp70. PLoS Genet. 2010 Jan;6(1):e1000807.   PMCID: PMC2795852
Arias-Romero LE, Saha S, Villamar-Cruz O, Yip SC, Ethier SP, Zhang ZY, Chernoff J. Activation of Src by protein tyrosine phosphatase 1B Is required for ErbB2 transformation of human breast epithelial cells. Cancer Res. 2009 Jun;69(11):4582-8.   PMCID: PMC2692630
Merkel G, Andrake MD, Ramcharan J, Skalka AM. Oligonucleotide-based assays for integrase activity. Methods (San Diego, Calif). 2009 Apr;47(4):243-8.   PMCID: PMC2743288
Miller KA, Yeager N, Baker K, Liao XH, Refetoff S, Di Cristofano A. Oncogenic Kras requires simultaneous PI3K signaling to induce ERK activation and transform thyroid epithelial cells in vivo. Cancer Res. 2009 Apr 15;69(8):3689-94.   PMCID: PMC2669852
Makhov P, Golovine K, Uzzo RG, Rothman J, Crispen PL, Shaw T, Scoll BJ, Kolenko VM. Zinc chelation induces rapid depletion of the X-linked inhibitor of apoptosis and sensitizes prostate cancer cells to TRAIL-mediated apoptosis. Cell death and differentiation. 2008 Nov;15(11):1745-51.   PMCID: PMC2585550
Srimathi T, Robbins SL, Dubas RL, Chang H, Cheng H, Roder H, Park YC. Mapping of POP1-binding site on pyrin domain of ASC. The Journal of biological chemistry. 2008 May 30;283(22):15390-8.
Pugacheva EN, Jablonski SA, Hartman TR, Henske EP, Golemis EA. HEF1-dependent Aurora A activation induces disassembly of the primary cilium.[see comment]. Cell. 2007 Jun 29;129(7):1351-63.
Bellacosa A, Kumar CC, Di Cristofano A, Testa JR. Activation of AKT kinases in cancer: implications for therapeutic targeting. Advances in cancer research. 2005 Jan;94:29-86.
Findlay VJ, Townsend DM, Saavedra JE, Buzard GS, Citro ML, Keefer LK, Ji X, Tew KD. Tumor cell responses to a novel glutathione S-transferase-activated nitric oxide-releasing prodrug. Molecular Pharmacology. 2004 May;65(5):1070-9.
Altomare DA, Tanno S, De Rienzo A, Klein-Szanto AJ, Skele KL, Hoffman JP, Testa JR. Frequent activation of AKT2 kinase in human pancreatic carcinomas. Journal of cellular biochemistry. 2003 Jan;88(1):470-6.
Dadke D, Fryer BH, Golemis EA, Field J. Activation of p21-activated kinase 1-nuclear factor kappaB signaling by Kaposi's sarcoma-associated herpes virus G protein-coupled receptor during cellular transformation. Cancer Res. 2003 Dec 15;63(24):8837-47.
Taylor JC, Markham GD. Conformational dynamics of the active site loop of S-adenosylmethionine synthetase illuminated by site-directed spin labeling. Archives of biochemistry and biophysics. 2003 Jul 15;415(2):164-71.
Kandel ES, Skeen J, Majewski N, Di Cristofano A, Pandolfi PP, Feliciano CS, Gartel A, Hay N. Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage. Mol Cell Biol. 2002 Nov;22(22):7831-41.
Pan ZZ, Bruening W, Giasson BI, Lee VM, Godwin AK. Gamma-synuclein promotes cancer cell survival and inhibits stress- and chemotherapy drug-induced apoptosis by modulating MAPK pathways. The Journal of biological chemistry. 2002 Sep 20;277(38):35050-60.
The above publications are sorted by year, faculty last name, and first author. Click on any highlighted author listed to find all publications attributed to that individual. Click on the publication title to see the abstract. First authors who are faculty are highlighted like this. Last authors who are faculty are highlighted like this. Other authors who are faculty are highlighted like this.

MeSH cloud from publications including the MeSH term Enzyme Activation

Enzyme Activation metabolism Signal Transduction enzymology Mice physiology chemistry genetics pathology US Gov't Support-PHS Protein-Serine-Threonine Kinases Epithelial Cells Phosphorylation pharmacology Non-US Gov't Support 1-Phosphatidylinositol 3-Kinase drug effects MAP Kinase Signaling System NF-kappa B Cell Line Proto-Oncogene Proteins p21-Activated Kinases Neoplastic Cell Transformation drug therapy Cultured Cells methods Apoptosis Human Enzyme Inhibitors Proteasome Endopeptidase Complex pd [Pharmacology] Secondary Protein Structure Phosphoric Monoester Hydrolases Cell Division Western Blotting Cell Survival me [Metabolism] Inflammation Rats p38 Mitogen-Activated Protein Kinases Female Animal Disease Models Tertiary Protein Structure Cultured Tumor Cells Neoplasm Drug Resistance Biological Models Mutation Molecular Models Signal Transducing Adaptor Proteins JNK Mitogen-Activated Protein Kinases immunology de [Drug Effects] Neoplasms Proto-Oncogene Proteins pp60(c-src) Mitogen-Activated Protein Kinases Proto-Oncogene Proteins c-akt cytology Phosphoproteins Tumor Cell Line Protein Binding Tumor Suppressor Proteins Pyrazines kinase SCID Mice Precipitin Tests Saccharomyces cerevisiae Air Pollutants Up-Regulation Zinc Proto-Oncogene Proteins c-yes 0 (Nitric Oxide Donors) EC 2-5-1-18 (glutathione S-transferase pi) Cytokine Receptor gp130 Apoptosis Regulatory Proteins EC 2-7-1-37 (Protein-Serine-Threonine Kinases) 72025-60-6 (Leukotriene C4) Cytoskeleton Melanoma human) 0 (NEDD9 protein G-Protein-Coupled Receptors 4-Aminobenzoic Acid Protein p53 3T3 Cells 10102-43-9 (Nitric Oxide) Prodrugs 4-dinitro-5-(N-methyl-N-4-carboxyphenylamino)phenyl 0 (O(2)-(2 CDC2 Protein Kinase Small Interfering RNA Human Herpesvirus 8 Fibroblasts Recombinant Fusion Proteins Homeostasis aa [Analogs & Derivatives] 2-diolate) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1 Chelating Agents Nitric Oxide 4-dinitrophenyl) 0 (O(2)-(2 Caspase 1 DNA Repair Proto-Oncogene Proteins p21(ras) Ozone cdc42 GTP-Binding Protein HIV-1 150-13-0 (4-Aminobenzoic Acid) Binding Sites Gamma Rays Oligonucleotide Array Sequence Analysis Immunohistochemistry Piperazines Kinetics Site-Directed Mutagenesis Pancreatic Neoplasms Spin Labels ai [Antagonists & Inhibitors] beta Catenin deficiency Proto-Oncogene Proteins c-bcl-2 Prostatic Neoplasms Carrier Proteins Ethylamines S-Adenosylmethionine therapy Multidrug Resistance-Associated Proteins etiology Protein Transport Non-Receptor Type 1 Protein Tyrosine Phosphatase airway EC 3-5-1 (Histone Deacetylases) 0 (Phosphoproteins) Isoenzymes Virus Diseases N-dimethylamino)diazen-1-ium-1 1-N-2-diolate) ul [Ultrastructure] TOR Serine-Threonine Kinases Adenocarcinoma HEK293 Cells 0 (Isoenzymes) Inflammatory Bowel Diseases ge [Genetics] 0 (Multidrug Resistance-Associated Proteins) Viral Cell Transformation Pancreas cdc Genes Multiprotein Complexes Body Weight Thyroid Gland Sulfones 0 (Piperazines) Recombinant Proteins US Gov't Support-Non-PHS
Last updated on Monday, May 04, 2020