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Publication Listing for the MeSH term Drug Design. Found 14 abstracts

Wodak SJ, Paci E, Dokholyan NV, Berezovsky IN, Horovitz A, Li J, Hilser VJ, Bahar I, Karanicolas J, Stock G, Hamm P, Stote RH, Eberhardt J, Chebaro Y, Dejaegere A, Cecchini M, Changeux JP, Bolhuis PG, Vreede J, Faccioli P, Orioli S, Ravasio R, Yan L, Brito C, Wyart M, Gkeka P, Rivalta I, Palermo G, McCammon JA, Panecka-Hofman J, Wade RC, Di Pizio A, Niv MY, Nussinov R, Tsai CJ, Jang H, Padhorny D, Kozakov D, McLeish T. Allostery in Its Many Disguises: From Theory to Applications. Structure (London, England : 1993). 2019 Apr 02;27(4):566-78.   PMCID: PMC6688844
Adolf-Bryfogle J, Kalyuzhniy O, Kubitz M, Weitzner BD, Hu X, Adachi Y, Schief WR, Dunbrack RL. RosettaAntibodyDesign (RAbD): A general framework for computational antibody design. PLoS computational biology. 2018 Apr 27;14(4):e1006112.   PMCID: PMC5942852
Pal RK, Haider K, Kaur D, Flynn W, Xia J, Levy RM, Taran T, Wickstrom L, Kurtzman T, Gallicchio E. A combined treatment of hydration and dynamical effects for the modeling of host-guest binding thermodynamics: the SAMPL5 blinded challenge. Journal of computer-aided molecular design. 2017 Jan;31(1):29-44.   PMCID: PMC5477994
Deng N, Flynn WF, Xia J, Vijayan RS, Zhang B, He P, Mentes A, Gallicchio E, Levy RM. Large scale free energy calculations for blind predictions of protein-ligand binding: the D3R Grand Challenge 2015. Journal of computer-aided molecular design. 2016 Sep;30(9):743-51.
Wakefield AE, Wuest WM, Voelz VA. Molecular Simulation of Conformational Pre-Organization in Cyclic RGD Peptides. Journal of chemical information and modeling. 2015 Apr 27;55(4):806-13.
Anastassiadis T, Duong-Ly KC, Deacon SW, Lafontant A, Ma H, Devarajan K, Dunbrack RL, Wu J, Peterson JR. A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-regulated kinase (ERK) inhibitor. The Journal of biological chemistry. 2013 Sep 27;288(39):28068-77.   PMCID: PMC3784719
Reitz AB, Smith GR, Tounge BA, Reynolds CH. Hit triage using efficiency indices after screening of compound libraries in drug discovery. Curr Top Med Chem. 2009 Jan;9(18):1718-24.
Borghaei H, Binyamin L, Astsaturov I, Weiner AM. Antibody therapy of cancer. In: Kaufman HL, Wadler S, Antman K, editors. Molecular targeting in oncology. Totowa, N.J.: Humana Press; 2008. p. 371-.
Lawrence SH, Ramirez UD, Tang L, Fazliyez F, Kundrat L, Markham GD, Jaffe EK. Shape shifting leads to small-molecule allosteric drug discovery. Chem Biol. 2008 Jun;15(6):586-96.
Bao KK, Wang H, Miller JK, Erie DA, Skalka AM, Wong I. Functional oligomeric state of avian sarcoma virus integrase. The Journal of biological chemistry. 2003 Jan 10;278(2):1323-7.
Golemis EA, Tew KD, Dadke D. Protein interaction-targeted drug discovery: evaluating critical issues. Biotechniques. 2002 Mar;32(3):636-8, 640, 642 passim.
Adams GP, Weiner LM. Radioimmunotherapy of solid tumors: from fairytale to reality. Cancer Biother Radiopharm. 2001 Feb;16(1):9-11.
Golemis EA, Ochs MF, Pugacheva EN. Signal transduction driving technology driving signal transduction: factors in the design of targeted therapies. J Cell Biochem Suppl. 2001 Jan;Suppl 37:42-52.
Hudes GR, Schol J. Phase I trial of oral R115777 in patients with refractory solid tumors: preliminary results. In: Sebti SM, Hamilton AD, editors. Farnesyltransferase inhibitors in cancer therapy. Totowa, N.J.: Humana Press; 2001. p. 251-4.
The above publications are sorted by year, faculty last name, and first author. Click on any highlighted author listed to find all publications attributed to that individual. Click on the publication title to see the abstract. First authors who are faculty are highlighted like this. Last authors who are faculty are highlighted like this. Other authors who are faculty are highlighted like this.

MeSH cloud from publications including the MeSH term Drug Design

Drug Design chemistry Protein Conformation methods Thermodynamics metabolism Binding Sites US Gov't Support-PHS Molecular Dynamics Simulation pharmacology Ligands immunology physiology Non-US Gov't Support Signal Transduction Molecular Weight Amino Acid Sequence Allosteric Site genetics Proteins Molecular Models Protein Binding Human Gene Expression Regulation Proteome Molecular Conformation elastic network models Protein-Tyrosine Kinase Water Pyridazines Directed Molecular Evolution Immunoglobulin Fragments Adenosine Triphosphate Time Factors Radioimmunodetection Pharmaceutical Chemistry Protein Databases Prospective Studies signal transduction Iodine Radioisotopes Computer Simulation Avian Sarcoma Viruses Dimethylallyltranstransferase antagonists & inhibitors Structure-Activity Relationship Protein Engineering Preclinical Drug Evaluation drug effects Phosphoproteins Neoplasm Antibodies Cellular Apoptosis Susceptibility Protein Phosphorylation Cyclic Peptides Neoplasms Molecular Sequence Data allosteric drugs Animal Allosteric Regulation Monoclonal Antibodies Antineoplastic Agents chemical synthesis statistics & numerical data allosteric switches Pharmaceutical Technology Chimeric Proteins molecular dynamics Software Salt effects Integrase Inhibitors ROC Curve Peptidomimetics Sampl5 Debye-Huckel Catalysis Protein Kinase Inhibitors Cricetulus Roc Antineoplastic Agents therapeutic use Protein Interaction Mapping Amino Acid Sequence Homology Hsp90 Antigen-Antibody Complex Carcinoembryonic Antigen Drug Discovery radiotherapy Enzyme Inhibitors therapeutic use D3r Molecular Structure Agbnp2 Binding free energy ras Genes allosteric material Mutation classification regulation Antibody Affinity Pyrazoles energy landscape enzymology Antigen-Antibody Reactions Molecular Docking Simulation Genetic Transcription Antineoplastic Agents pharmacology Drug Dose-Response Relationship Neoplasm Antigens Radioimmunotherapy Dimerization Hydration Site Analysis (HSA) Antibodies Computational Biology Metabolic Networks and Pathways Allostery MAP Kinase Signaling System CHO Cells Atomic Force Microscopy Drug Delivery Systems diagnostic use Complementarity Determining Regions Solvents Drug Evaluation Bedam Monte Carlo Method protein conformational changes IGF Type 1 Receptor Magnetic Resonance Spectroscopy Theoretical Models pharmacokinetics Biosensing Techniques Integrase Forecasting HSP90 Heat-Shock Proteins Eukaryotic Cells radionuclide imaging Docking Neoplasms drug therapy Fluorine Radioisotopes Small Molecule Libraries Structural Models therapeutic use Insulin Receptor Gc2015 Mice Radiopharmaceuticals Antiviral Agents X-Ray Crystallography protein function Information Management Kinetics
Last updated on Thursday, April 02, 2020