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Publication Listing for the MeSH term Cystathionine beta-Synthase. Found 12 abstracts

Cheng Z, Jiang X, Pansuria M, Fang P, Mai J, Mallilankaraman K, Gandhirajan RK, Eguchi S, Scalia R, Madesh M, Yang X, Wang H. Hyperhomocysteinemia and hyperglycemia induce and potentiate endothelial dysfunction via mu-calpain activation. Diabetes. 2015 Mar;64(3):947-59.   PMCID: PMC4338586
Singh LR, Gupta S, Honig NH, Kraus JP, Kruger WD. Activation of mutant enzyme function in vivo by proteasome inhibitors and treatments that induce Hsp70. PLoS Genet. 2010 Jan;6(1):e1000807.   PMCID: PMC2795852
Gupta S, Kuhnisch J, Mustafa A, Lhotak S, Schlachterman A, Slifker MJ, Klein-Szanto A, High KA, Austin RC, Kruger WD. Mouse models of cystathionine beta-synthase deficiency reveal significant threshold effects of hyperhomocysteinemia. FASEB J. 2009 Mar;23(3):883-93.   PMCID: PMC2653989
Singh LR, Kruger WD. Functional rescue of mutant human cystathionine beta-synthase by manipulation of Hsp26 and Hsp70 levels in Saccharomyces cerevisiae. J Biol Chem. 2009 Feb 13;284(7):4238-45.   PMCID: PMC2640983
Gupta S, Wang L, Hua X, Krijt J, Kozich V, Kruger WD. Cystathionine beta-synthase p.S466L mutation causes hyperhomocysteinemia in mice. Hum Mutat. 2008 Aug;29(8):1048-54.   PMCID: PMC2630375
Wang L, Jhee KH, Hua X, DiBello PM, Jacobsen DW, Kruger WD. Modulation of cystathionine beta-synthase level regulates total serum homocysteine in mice. Circ Res. 2004 May 28;94(10):1318-24.
Christopher SA, Melnyk S, James SJ, Kruger WD. S-adenosylhomocysteine, but not homocysteine, is toxic to yeast lacking cystathionine beta-synthase. Mol Genet Metab. 2002 Apr;75(4):335-43.
Guttormsen AB, Ueland PM, Kruger WD, Kim CE, Ose L, Folling I, Refsum H. Disposition of homocysteine in subjects heterozygous for homocystinuria due to cystathionine beta-synthase deficiency: relationship between genotype and phenotype. Am J Med Genet. 2001 May;100(3):204-13.
Nozaki T, Shigeta Y, Saito-Nakano Y, Imada M, Kruger WD. Characterization of transsulfuration and cysteine biosynthetic pathways in the protozoan hemoflagellate, Trypanosoma cruzi. Isolation and molecular characterization of cystathionine beta-synthase and serine acetyltransferase from Trypanosoma. J Biol Chem. 2001 Mar 02;276(9):6516-23.
Shan X, Dunbrack RL, Christopher SA, Kruger WD. Mutations in the regulatory domain of cystathionine beta synthase can functionally suppress patient-derived mutations in cis. Hum Mol Genet. 2001 Mar 15;10(6):635-43.
Kruger WD, Evans AA, Wang L, Malinow MR, Duell PB, Anderson PH, Block PC, Hess DL, Graf EE, Upson B. Polymorphisms in the CBS gene associated with decreased risk of coronary artery disease and increased responsiveness to total homocysteine lowering by folic acid. Mol Genet Metab. 2000 May;70(1):53-60.
Shan X, Kruger WD. Correction of disease-causing CBS mutations in yeast. Nat Genet. 1998 May;19(1):91-3.
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MeSH cloud from publications including the MeSH term Cystathionine beta-Synthase

Cystathionine beta-Synthase genetics metabolism Non-US Gov't Support Homocystinuria Human Mice US Gov't Support-PHS Homocysteine Saccharomyces cerevisiae enzymology Mutation Male drug effects blood Hyperhomocysteinemia Methionine pathology Transgenic Mice pharmacology Genotype HSP70 Heat-Shock Proteins Molecular Sequence Data drug therapy Cultured Cells therapy Liver Female Enzymologic Gene Expression Regulation Gene Expression Amino Acid Sequence Protein Folding Phenotype Proteasome Endopeptidase Complex deficiency Middle Age S-Adenosylmethionine Myocardium 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase Blood Glucose Osteoporosis Treatment Outcome biosynthesis Trypanosoma cruzi analysis Amine Oxidoreductases Analysis of Variance Mutagenesis Gene Knockdown Techniques Ubiquitin physiopathology Inbred C57BL Mice Animal Endoplasmic Reticulum ge [Genetics] Aorta Haplotypes me [Metabolism] Multiprotein Complexes Amino Acids Adolescent Recombinant Proteins Mutant Strains Mice Amino Acid Sequence Homology Knockout Mice DNA Pyrazines Endothelial Cells Ethanol Longevity Coronary Disease Folic Acid Complementary DNA Protein Conformation Saccharomyces cerevisiae Proteins Heterozygote urine Cysteine Enzyme Activation Protein Binding chemistry bl [Blood] Polymorphism (Genetics) Cysteine Synthase Adult inhibitors Genetic Predisposition to Disease Risk Factors 0 (Amino Acids) Gene Expression Profiling Reference Values Acetyltransferases physiology Genetic Screening Fungal Proteins Superoxides toxicity Fibroblasts 63-68-3 (Methionine) Solvents Molecular Models Amino Acid Substitution Aged Heat-Shock Proteins secretion 454-28-4 (Homocysteine) EC 4-2-1-22 (Cystathionine beta-Synthase) Cell Line Calpain Cystathionine therapeutic use Gene Therapy administration & dosage Tertiary Protein Structure Boronic Acids antagonists & Oligonucleotide Array Sequence Analysis Enzyme Inhibitors Hyperglycemia Animal Disease Models isolation & purification Missense Mutation Culture Media High Pressure Liquid Chromatography Yeasts growth & development Nitric Oxide Synthase Type III S-Adenosylhomocysteine
Last updated on Wednesday, May 13, 2015