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Publication Listing for the MeSH term Cystathionine beta-Synthase. Found 14 abstracts

Gupta S, Wang L, Kruger WD. Betaine supplementation is less effective than methionine restriction in correcting phenotypes of CBS deficient mice. J Inherit Metab Dis. 2016 Jan;39(1):39-46.   PMCID: PMC4784539
Xi H, Zhang Y, Xu Y, Yang WY, Jiang X, Sha X, Cheng X, Wang J, Qin X, Yu J, Ji Y, Yang X, Wang H. Caspase-1 Inflammasome Activation Mediates Homocysteine-Induced Pyrop-Apoptosis in Endothelial Cells. Circulation research. 2016 May 13;118(10):1525-39.   PMCID: PMC4867131
Nelson J, Wu Y, Jiang X, Berretta R, Houser S, Choi E, Wang J, Huang J, Yang X, Wang H. Hyperhomocysteinemia suppresses bone marrow CD34+/VEGF receptor 2+ cells and inhibits progenitor cell mobilization and homing to injured vasculature-a role of beta1-integrin in progenitor cell migration and adhesion. FASEB J. 2015 Jul;29(7):3085-99.   PMCID: PMC4478803
Singh LR, Gupta S, Honig NH, Kraus JP, Kruger WD. Activation of mutant enzyme function in vivo by proteasome inhibitors and treatments that induce Hsp70. PLoS Genet. 2010 Jan;6(1):e1000807.   PMCID: PMC2795852
Gupta S, Kuhnisch J, Mustafa A, Lhotak S, Schlachterman A, Slifker MJ, Klein-Szanto A, High KA, Austin RC, Kruger WD. Mouse models of cystathionine beta-synthase deficiency reveal significant threshold effects of hyperhomocysteinemia. FASEB J. 2009 Mar;23(3):883-93.   PMCID: PMC2653989
Singh LR, Kruger WD. Functional rescue of mutant human cystathionine beta-synthase by manipulation of Hsp26 and Hsp70 levels in Saccharomyces cerevisiae. The Journal of biological chemistry. 2009 Feb 13;284(7):4238-45.   PMCID: PMC2640983
Gupta S, Wang L, Hua X, Krijt J, Kozich V, Kruger WD. Cystathionine beta-synthase p.S466L mutation causes hyperhomocysteinemia in mice. Hum Mutat. 2008 Aug;29(8):1048-54.   PMCID: PMC2630375
Wang L, Jhee KH, Hua X, DiBello PM, Jacobsen DW, Kruger WD. Modulation of cystathionine beta-synthase level regulates total serum homocysteine in mice. Circulation research. 2004 May 28;94(10):1318-24.
Christopher SA, Melnyk S, James SJ, Kruger WD. S-adenosylhomocysteine, but not homocysteine, is toxic to yeast lacking cystathionine beta-synthase. Molecular genetics and metabolism. 2002 Apr;75(4):335-43.
Guttormsen AB, Ueland PM, Kruger WD, Kim CE, Ose L, Folling I, Refsum H. Disposition of homocysteine in subjects heterozygous for homocystinuria due to cystathionine beta-synthase deficiency: relationship between genotype and phenotype. Am J Med Genet. 2001 May;100(3):204-13.
Nozaki T, Shigeta Y, Saito-Nakano Y, Imada M, Kruger WD. Characterization of transsulfuration and cysteine biosynthetic pathways in the protozoan hemoflagellate, Trypanosoma cruzi. Isolation and molecular characterization of cystathionine beta-synthase and serine acetyltransferase from Trypanosoma. The Journal of biological chemistry. 2001 Mar 02;276(9):6516-23.
Shan X, Dunbrack RL, Christopher SA, Kruger WD. Mutations in the regulatory domain of cystathionine beta synthase can functionally suppress patient-derived mutations in cis. Human molecular genetics. 2001 Mar 15;10(6):635-43.
Kruger WD, Evans AA, Wang L, Malinow MR, Duell PB, Anderson PH, Block PC, Hess DL, Graf EE, Upson B. Polymorphisms in the CBS gene associated with decreased risk of coronary artery disease and increased responsiveness to total homocysteine lowering by folic acid. Molecular genetics and metabolism. 2000 May;70(1):53-60.
Shan X, Kruger WD. Correction of disease-causing CBS mutations in yeast. Nature genetics. 1998 May;19(1):91-3.
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MeSH cloud from publications including the MeSH term Cystathionine beta-Synthase

Cystathionine beta-Synthase genetics metabolism Mice Homocystinuria Human Homocysteine Non-US Gov't Support US Gov't Support-PHS Saccharomyces cerevisiae drug effects Male enzymology Mutation Inbred C57BL Mice Female deficiency Animal Disease Models blood Methionine Transgenic Mice Hyperhomocysteinemia drug therapy Phenotype Amino Acid Sequence administration & dosage Molecular Sequence Data Liver pathology Middle Age Protein Folding HSP70 Heat-Shock Proteins Osteoporosis Enzymologic Gene Expression Regulation physiology pharmacology Genotype therapy Gene Expression Proteasome Endopeptidase Complex toxicity Analysis of Variance Gene Knockdown Techniques Ubiquitin Mutagenesis methods physiopathology pyroptosis homocysteine Animal Endoplasmic Reticulum ge [Genetics] Aorta me [Metabolism] Haplotypes Multiprotein Complexes Amino Acids Neointima Pyroptosis Adolescent apoptosis Recombinant Proteins Vascular Remodeling Inflammasomes Amino Acid Sequence Homology Knockout Mice endothelial cells DNA Pyrazines Ethanol Longevity Coronary Disease bcl-2-Associated X Protein Folic Acid CD34 Antigens Bone Density Complementary DNA cell therapy Saccharomyces cerevisiae Proteins Protein Conformation Cysteine Heterozygote urine Enzyme Activation Human Umbilical Vein Endothelial Cells Protein Binding bl [Blood] Cysteine Synthase Polymorphism (Genetics) Adult inhibitors Genetic Predisposition to Disease 0 (Amino Acids) Risk Factors Carotid Artery Injuries Reactive Oxygen Species Acetyltransferases Reference Values CD29 Antigens Gene Expression Profiling Bone Marrow Cells Genetic Screening Betaine Fibroblasts 63-68-3 (Methionine) Dietary Supplements Solvents Molecular Models Caspase 1 Colony-Forming Units Assay endothelial repair 454-28-4 (Homocysteine) secretion EC 4-2-1-22 (Cystathionine beta-Synthase) Cell Line Weight Loss chemistry Oligonucleotide Array Sequence Analysis Fungal Proteins Vascular Endothelial Growth Factor Receptor-2 Green Fluorescent Proteins Amino Acid Substitution Aged Heat-Shock Proteins Hematopoietic Stem Cells Cystathionine therapeutic use Gene Therapy Boronic Acids Tertiary Protein Structure antagonists & Cell Movement Enzyme Inhibitors Hematopoietic Stem Cell Transplantation Lipopolysaccharides isolation & purification prevention & control Missense Mutation Interleukin-1beta Diet Culture Media Cell Adhesion High Pressure Liquid Chromatography Yeasts growth & development S-Adenosylhomocysteine S-Adenosylmethionine Myocardium 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase Pyrin Domain-Containing 3 Protein NLR Family
Last updated on Thursday, July 16, 2020