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Publication Listing for the MeSH term Antitumor Drug Screening Assays. Found 20 abstracts

Stromyer ML, Southerland MR, Satyal U, Sikder RK, Weader DJ, Baughman JA, Youngs WJ, Abbosh PH. Synthesis, characterization, and biological activity of a triphenylphosphonium-containing imidazolium salt against select bladder cancer cell lines. European journal of medicinal chemistry. 2020 Jan;185:111832.
Galal Osman A, Elokely KM, Yadav VK, Carvalho P, Radwan M, Slade D, Gul W, Khan S, Dale OR, Husni AS, Klein ML, Cutler SJ, Ross SA, ElSohly MA. Bioactive products from singlet oxygen photooxygenation of cannabinoids. European journal of medicinal chemistry. 2018 Jan;143:983-96.
de Oliveira JF, Lima TS, Vendramini-Costa DB, de Lacerda Pedrosa SC, Lafayette EA, da Silva RM, de Almeida SM, de Moura RO, Ruiz A, de Carvalho JE, de Lima M. Thiosemicarbazones and 4-thiazolidinones indole-based derivatives: Synthesis, evaluation of antiproliferative activity, cell death mechanisms and topoisomerase inhibition assay. European journal of medicinal chemistry. 2017 Aug 18;136:305-14.
Huang F, Goyal N, Sullivan K, Hanamshet K, Patel M, Mazina OM, Wang CX, An WF, Spoonamore J, Metkar S, Emmitte KA, Cocklin S, Skorski T, Mazin AV. Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitors. Nucleic acids research. 2016 May 19;44(9):4189-99.   PMCID: PMC4872086
Allen JE, Krigsfeld G, Patel L, Mayes PA, Dicker DT, Wu GS, El-Deiry WS. Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway. Mol Cancer. 2015 May;14(1):99.   PMCID: 4428111
Allen JE, Prabhu VV, Talekar M, van den Heuvel AP, Lim B, Dicker DT, Fritz JL, Beck A, El-Deiry WS. Genetic and Pharmacological Screens Converge in Identifying FLIP, BCL2, and IAP Proteins as Key Regulators of Sensitivity to the TRAIL-Inducing Anticancer Agent ONC201/TIC10. Cancer Res. 2015 Apr 15;75(8):1668-74.   PMCID: PMC4541796
Motzer RJ, Hutson TE, Hudes GR, Figlin RA, Martini JF, English PA, Huang X, Valota O, Williams JA. Investigation of novel circulating proteins, germ line single-nucleotide polymorphisms, and molecular tumor markers as potential efficacy biomarkers of first-line sunitinib therapy for advanced renal cell carcinoma. Cancer Chemother Pharmacol. 2014 Oct;74(4):739-50.   PMCID: 4175044
Golovine KV, Makhov PB, Teper E, Kutikov A, Canter D, Uzzo RG, Kolenko VM. Piperlongumine induces rapid depletion of the androgen receptor in human prostate cancer cells. The Prostate. 2013 Jan;73(1):23-30.   PMCID: PMC3491117
Makhov P, Golovine K, Uzzo RG, Rothman J, Crispen PL, Shaw T, Scoll BJ, Kolenko VM. Zinc chelation induces rapid depletion of the X-linked inhibitor of apoptosis and sensitizes prostate cancer cells to TRAIL-mediated apoptosis. Cell death and differentiation. 2008 Nov;15(11):1745-51.   PMCID: PMC2585550
Serebriiskii I, Castello-Cros R, Lamb A, Golemis EA, Cukierman E. Fibroblast-derived 3D matrix differentially regulates the growth and drug-responsiveness of human cancer cells. Matrix biology : journal of the International Society for Matrix Biology. 2008 Jul;27(6):573-85.   PMCID: PMC2603546
Crispen PL, Uzzo RG, Golovine K, Makhov P, Pollack A, Horwitz EM, Greenberg RE, Kolenko VM. Vitamin E succinate inhibits NF-kappaB and prevents the development of a metastatic phenotype in prostate cancer cells: implications for chemoprevention. The Prostate. 2007 May;67(6):582-90.
Rahimipour S, Litichever-Coslovsky N, Alaluf M, Freeman D, Ehrenberg B, Weiner L, Mazur Y, Fridkin M, Koch Y. Novel methyl helianthrones as photosensitizers: synthesis and biological evaluation. Photochemistry and Photobiology. 2005 Mar;81(2):250-8.
Ma J, Murphy M, O'Dwyer PJ, Berman E, Reed K, Gallo JM. Biochemical changes associated with a multidrug-resistant phenotype of a human glioma cell line with temozolomide-acquired resistance. Biochemical pharmacology. 2002 Apr;63(7):1219-28.
Scotto KW. ET-743: more than an innovative mechanism of action. Anticancer Drugs. 2002 May;13 Suppl 1:S3-6.
Bao R, Selvakumaran M, Hamilton TC. Use of a surrogate marker (human secreted alkaline phosphatase) to monitor in vivo tumor growth and anticancer drug efficacy in ovarian cancer xenografts. Gynecol Oncol. 2000 Sep;78(3 Pt 1):373-9.
Lee K, Klein-Szanto AJ, Kruh GD. Analysis of the MRP4 drug resistance profile in transfected NIH3T3 cells. Journal of the National Cancer Institute. 2000 Dec 06;92(23):1934-40.
O'Brien M, Kruh GD, Tew KD. The influence of coordinate overexpression of glutathione phase II detoxification gene products on drug resistance. The Journal of pharmacology and experimental therapeutics. 2000 Aug;294(2):480-7.
Rosario LA, O'Brien ML, Henderson CJ, Wolf CR, Tew KD. Cellular response to a glutathione S-transferase P1-1 activated prodrug. Mol Pharmacol. 2000 Jul;58(1):167-74.
Hudes G. Estramustine-based chemotherapy. Semin Urol Oncol. 1997 Feb;15(1):13-9.
Zhang X, Minale L, Zampella A, Smith CD. Microfilament depletion and circumvention of multiple drug resistance by sphinxolides. Cancer Res. 1997 Sep;57(17):3751-8.
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MeSH cloud from publications including the MeSH term Antitumor Drug Screening Assays

Antitumor Drug Screening Assays pharmacology metabolism Antineoplastic Agents drug effects Tumor Cell Line Mice chemistry genetics Human Male US Gov't Support-PHS Cell Survival Cultured Tumor Cells Animal drug therapy Non-US Gov't Support Prostatic Neoplasms chemical synthesis Cell Proliferation physiology pathology 3T3 Cells Molecular Structure Female Apoptosis Phytogenic Antineoplastic Agents antagonists & inhibitors Neoplasm Drug Resistance Multiple Drug Resistance Drug Dose-Response Relationship Transfection Alkylating Antineoplastic Agents Complementary DNA NF-kappa B Singlet Oxygen enzymology pd [Pharmacology] 0 (Neoplasm Proteins) Structure-Activity Relationship Neoplasm Antigens HL-60 Cells Neoplasm Proteins Small Molecule Libraries Glutathione Proteasome Endopeptidase Complex administration & dosage Glutathione Transferase Isoenzymes TNF-Related Apoptosis-Inducing Ligand Reactive Oxygen Species pharmacokinetics methods Adenosinetriphosphatase Biological Tumor Markers Proto-Oncogene Proteins c-bcl-2 Type II DNA Topoisomerases me [Metabolism] analogs & derivatives Polymers Inhibitory Concentration 50 Indoles Cytotoxins de [Drug Effects] Heterocyclic Compounds with 4 or More Rings Fibroblasts Reporter Genes Vitamin E blood aa [Analogs & Derivatives] Cell Cycle Paclitaxel DNA-Binding Proteins pa [Pathology] Phenotype therapeutic use Molecular Cloning EC 2-1-1-63 (O(6)-Methylguanine-DNA Methyltransferase) 85622-93-1 (temozolomide) Glioma Angiogenesis Inhibitors Alkylating) 0 (Antineoplastic Agents 0 (Cyclins) Enzyme Activation Adult Protein p53 Vascular Endothelial Growth Factor A Prodrugs Transcription Factor AP-1 CD29 Antigens Porifera HCT116 Cells Photooxygenation Small Interfering RNA toxicity 33069-62-4 (Paclitaxel) Cisplatin 23214-92-8 (Doxorubicin) Organophosphorus Compounds mammalian) 0 (MLH1 protein Smooth Muscle-Vascular Anticancer therapy 4342-03-4 (Dacarbazine) Molecular Models Thiosemicarbazones Chelating Agents Hep G2 Cells Clinical Trials Cell Line Cytochalasin B Fungi Luciferases Cyclins Experimental Neoplasms Immunohistochemistry Oxidative Stress Dacarbazine ai [Antagonists & Inhibitors] Ubiquitin-Protein Ligases Tumor Biomarkers DNA Repair Enzymes Cell Adhesion Anthracenes deficiency EC 3-6-1-3 (Adenosinetriphosphatase) Antiprotozoal Agents Nude Mice Topoisomerase inhibition Drug Interactions Carrier Proteins Acrylates Biological Models Ethylamines Angiopoietin-2 Pyrroles Multidrug Resistance-Associated Proteins Cannabinoid Receptor-CB2 Imidazoles Anthracycline Antibiotics Microfilaments Treatment Outcome biosynthesis cytology EC 6-5-1 (DNA Repair Enzymes) Cultured Cells Plasmodium falciparum Topoisomerase Inhibitors Amino Acid Sequence Adenocarcinoma Alkaline Phosphatase
Last updated on Tuesday, July 07, 2020