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Kruisbeek AM, Haks MC, Carleton M, Michie AM, Zuniga-Pflucker JC, Wiest DL
Branching out to gain control: how the pre-TCR is linked to multiple functions
Immunology Today (2000) 21:637-644.
How is signaling specificity achieved by the pre-TCR during selection of T-cell fate? Like the TCR, this receptor controls many functions, and recent studies define which pathways couple the pre-TCR to the molecular events controlling survival, proliferation, allelic exclusion at the TCR beta locus, and further differentiation.
Publication Date: 2000-12-01.
Last updated on Thursday, June 04, 2020