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Kruisbeek AM, Haks MC, Carleton M, Michie AM, Zuniga-Pflucker JC, Wiest DL
Branching out to gain control: how the pre-TCR is linked to multiple functions
Immunology Today (2000) 21:637-644.
Abstract
How is signaling specificity achieved by the pre-TCR during selection of T-cell fate? Like the TCR, this receptor controls many functions, and recent studies define which pathways couple the pre-TCR to the molecular events controlling survival, proliferation, allelic exclusion at the TCR beta locus, and further differentiation.
Note
Publication Date: 2000-12-01.
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Last updated on Thursday, August 02, 2018