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Prinsep MR, Patterson GM, Larsen LK, Smith CD
Tolyporphins J and K, two further porphinoid metabolites from the cyanobacterium Tolypothrix nodosa
Journal of Natural Products (1998) 61:1133-1136.
Two new porphinoids, tolyporphins J (1) and K (2), have been isolated from the terrestrial cyanobacterium, Tolypothrix nodosa (HT-58-2) and identified by NMR and mass spectral analysis. The activities of tolyporphins J and K in cell sensitization and drug accumulation assays for multidrug resistance (MDR) reversal were compared with those of tolyporphin A. Unusual NMR spectroscopic shifts were observed for tolyporphin J (1) in CDCl3.
Publication Date: 1998-09-01.
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